5WXF

Crystal structure of uPA in complex with upain-2-2

Summary for 5WXF

• Entry DOI: 10.2210/pdb5wxf/pdb
• Related: 5WXO 5WXP 5WXQ 5WXR 5WXS 5WXT
• Descriptor: Urokinase-type plasminogen activator chain B, upain-2-2 peptide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: serine proteases, upa, pepetide inhibitors, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 29899.97

Authors

Jiang, L.,Huang, M. (deposition date: 2017-01-07, release date: 2018-07-11, Last modification date: 2023-11-22)

• Primary citation: Jiang, L.,Oldenburg, E.,Kromann-Hansen, T.,Xu, P.,Jensen, J.K.,Andreasen, P.A.,Huang, M.; Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition.; Biochim. Biophys. Acta, 1862:2017-2023, 2018; PubMed: 29959058; DOI: 10.1016/j.bbagen.2018.06.016

Experimental method

X-RAY DIFFRACTION (1.46 Å)