4X1P
The crystal structure of mupain-1-17 in complex with murinised human uPA at pH4.6
Summary for 4X1P
Entry DOI | 10.2210/pdb4x1p/pdb |
Related | 4N1Q 4N1R 4N1S 4X0W 4X1N |
Descriptor | Urokinase-type plasminogen activator, MUPAIN-1-17, SULFATE ION, ... (6 entities in total) |
Functional Keywords | serine protease, peptidic inhibitor, upa, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted: P00749 |
Total number of polymer chains | 2 |
Total formula weight | 29594.64 |
Authors | Jiang, L.,Zhao, B.,Xu, P.,Andreasen, P.,Huang, M. (deposition date: 2014-11-25, release date: 2015-10-21, Last modification date: 2017-10-18) |
Primary citation | Jiang, L.,Zhao, B.,Xu, P.,Srensen, H.P.,Jensen, J.K.,Christensen, A.,Hosseini, M.,Nielsen, N.C.,Jensen, K.J.,Andreasen, P.A.,Huang, M. Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues. Int.J.Biochem.Cell Biol., 62:88-92, 2015 Cited by PubMed: 25744057DOI: 10.1016/j.biocel.2015.02.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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