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4X1P

The crystal structure of mupain-1-17 in complex with murinised human uPA at pH4.6

Summary for 4X1P
Entry DOI10.2210/pdb4x1p/pdb
Related4N1Q 4N1R 4N1S 4X0W 4X1N
DescriptorUrokinase-type plasminogen activator, MUPAIN-1-17, SULFATE ION, ... (6 entities in total)
Functional Keywordsserine protease, peptidic inhibitor, upa, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (Human)
More
Cellular locationSecreted: P00749
Total number of polymer chains2
Total formula weight29594.64
Authors
Jiang, L.,Zhao, B.,Xu, P.,Andreasen, P.,Huang, M. (deposition date: 2014-11-25, release date: 2015-10-21, Last modification date: 2017-10-18)
Primary citationJiang, L.,Zhao, B.,Xu, P.,Srensen, H.P.,Jensen, J.K.,Christensen, A.,Hosseini, M.,Nielsen, N.C.,Jensen, K.J.,Andreasen, P.A.,Huang, M.
Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues.
Int.J.Biochem.Cell Biol., 62:88-92, 2015
Cited by
PubMed: 25744057
DOI: 10.1016/j.biocel.2015.02.016
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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