6UUR

Human prion protein fibril, M129 variant

Summary for 6UUR

• Entry DOI: 10.2210/pdb6uur/pdb
• EMDB information: 20900
• Descriptor: Major prion protein (1 entity in total)
• Functional Keywords: amyloid, fibril, prion, filament, protein fibril, fiber, prp
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 10
• Total formula weight: 96857.71

Authors

Glynn, C.,Sawaya, M.R.,Ge, P.,Zhou, Z.H.,Rodriguez, J.A. (deposition date: 2019-10-31, release date: 2020-04-15, Last modification date: 2024-03-06)

• Primary citation: Glynn, C.,Sawaya, M.R.,Ge, P.,Gallagher-Jones, M.,Short, C.W.,Bowman, R.,Apostol, M.,Zhou, Z.H.,Eisenberg, D.S.,Rodriguez, J.A.; Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.; Nat.Struct.Mol.Biol., 27:417-423, 2020; PubMed: 32284600; DOI: 10.1038/s41594-020-0403-y

Experimental method

ELECTRON MICROSCOPY (3.5 Å)