6UUR
Human prion protein fibril, M129 variant
Summary for 6UUR
Entry DOI | 10.2210/pdb6uur/pdb |
EMDB information | 20900 |
Descriptor | Major prion protein (1 entity in total) |
Functional Keywords | amyloid, fibril, prion, filament, protein fibril, fiber, prp |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 10 |
Total formula weight | 96857.71 |
Authors | Glynn, C.,Sawaya, M.R.,Ge, P.,Zhou, Z.H.,Rodriguez, J.A. (deposition date: 2019-10-31, release date: 2020-04-15, Last modification date: 2024-03-06) |
Primary citation | Glynn, C.,Sawaya, M.R.,Ge, P.,Gallagher-Jones, M.,Short, C.W.,Bowman, R.,Apostol, M.,Zhou, Z.H.,Eisenberg, D.S.,Rodriguez, J.A. Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core. Nat.Struct.Mol.Biol., 27:417-423, 2020 Cited by PubMed: 32284600DOI: 10.1038/s41594-020-0403-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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