8DU2
HnRNPA2 D290V LCD PM1
Summary for 8DU2
| Entry DOI | 10.2210/pdb8du2/pdb |
| EMDB information | 27713 |
| Descriptor | Heterogeneous nuclear ribonucleoproteins A2/B1 (1 entity in total) |
| Functional Keywords | amyloid, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 10 |
| Total formula weight | 153917.75 |
| Authors | Eisenberg, D.S.,Lu, J.,Ge, P.,Boyer, D.R. (deposition date: 2022-07-26, release date: 2023-08-02, Last modification date: 2024-02-14) |
| Primary citation | Lu, J.,Ge, P.,Sawaya, M.R.,Hughes, M.P.,Boyer, D.R.,Cao, Q.,Abskharon, R.,Cascio, D.,Tayeb-Fligelman, E.,Eisenberg, D.S. Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation. J.Biol.Chem., 300:105531-105531, 2023 Cited by PubMed: 38072051DOI: 10.1016/j.jbc.2023.105531 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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