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7V0E
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BU of 7v0e by Molmil
Crystal structure of the macro-oligomeric form of DNMT3B methyltransferase domain.
Descriptor: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Gao, L, Lu, J, Song, J.
Deposit date:2022-05-10
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.27016377 Å)
Cite:Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations.
Nat Commun, 13, 2022
7L2C
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BU of 7l2c by Molmil
Crystallographic structure of neutralizing antibody 2-51 in complex with SARS-CoV-2 spike N-terminal domain (NTD)
Descriptor: 2-51 heavy chain, 2-51 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cerutti, G, Reddem, E.R, Shapiro, L.
Deposit date:2020-12-16
Release date:2021-02-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7L2E
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BU of 7l2e by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-18 heavy chain, ...
Authors:Cerutti, G, Shapiro, L.
Deposit date:2020-12-16
Release date:2021-03-24
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7L2F
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BU of 7l2f by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 5-24 in complex with prefusion SARS-CoV-2 spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-24 heavy chain, ...
Authors:Cerutti, G, Shapiro, L.
Deposit date:2020-12-16
Release date:2021-03-24
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7L2D
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BU of 7l2d by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 1-87 in complex with prefusion SARS-CoV-2 spike glycoprotein
Descriptor: 1-87 heavy chain, 1-87 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cerutti, G, Shapiro, L.
Deposit date:2020-12-16
Release date:2021-03-24
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7L57
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BU of 7l57 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-15
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rapp, M, Shapiro, L.
Deposit date:2020-12-21
Release date:2021-04-14
Last modified:2021-04-21
Method:ELECTRON MICROSCOPY (5.87 Å)
Cite:Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
Cell Rep, 35, 2021
7L56
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BU of 7l56 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-43
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2-43 variable domain heavy chain, ...
Authors:Rapp, M, Shapiro, L.
Deposit date:2020-12-21
Release date:2021-04-14
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
Cell Rep, 35, 2021
7L58
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BU of 7l58 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab H4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab H4 variable domain heavy chain, ...
Authors:Rapp, M, Shapiro, L.
Deposit date:2020-12-21
Release date:2021-04-14
Last modified:2021-04-21
Method:ELECTRON MICROSCOPY (5.07 Å)
Cite:Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
Cell Rep, 35, 2021
7LMM
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BU of 7lmm by Molmil
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2
Descriptor: DNA (cytosine-5)-methyltransferase 1,DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION
Authors:Ren, W, Song, J.
Deposit date:2021-02-05
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Nat Commun, 12, 2021
7LMK
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BU of 7lmk by Molmil
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3
Descriptor: DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION
Authors:Ren, W, Song, J.
Deposit date:2021-02-05
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.647 Å)
Cite:DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Nat Commun, 12, 2021
7LQV
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BU of 7lqv by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 4-8 Fab in complex with SARS-CoV-2 S2P spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-8 Heavy Chain, 4-8 Light chain, ...
Authors:Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
Deposit date:2021-02-15
Release date:2021-03-24
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite
Cell Host Microbe, 2021
7LQW
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BU of 7lqw by Molmil
Cryo-EM structure of NTD-directed neutralizing antibody 2-17 Fab in complex with SARS-CoV-2 S2P spike
Descriptor: 2-17 Heavy Chain, 2-17 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
Deposit date:2021-02-15
Release date:2021-03-24
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (4.47 Å)
Cite:Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cell Host Microbe, 29, 2021
7WKS
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BU of 7wks by Molmil
Apo state of AtPIN3
Descriptor: Auxin efflux carrier component 3
Authors:Su, N.
Deposit date:2022-01-11
Release date:2022-08-10
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
7WKW
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BU of 7wkw by Molmil
NPA bound state of AtPIN3
Descriptor: 2-(naphthalen-1-ylcarbamoyl)benzoic acid, Auxin efflux carrier component 3
Authors:Su, N.
Deposit date:2022-01-11
Release date:2022-08-10
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
7XXB
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BU of 7xxb by Molmil
IAA bound state of AtPIN3
Descriptor: 1H-INDOL-3-YLACETIC ACID, Auxin efflux carrier component 3
Authors:Su, N.
Deposit date:2022-05-29
Release date:2022-08-10
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Nature, 609, 2022
3GIZ
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BU of 3giz by Molmil
Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab
Descriptor: Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain, light chain, ...
Authors:Du, J, Yang, H, Ding, J.
Deposit date:2009-03-07
Release date:2009-05-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20
Mol.Immunol., 46, 2009
6M17
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BU of 6m17 by Molmil
The 2019-nCoV RBD/ACE2-B0AT1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, R.H, Zhang, Y.Y, Li, Y.N, Xia, L, Guo, Y.Y, Zhou, Q.
Deposit date:2020-02-24
Release date:2020-03-11
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2.
Science, 367, 2020
3KPH
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BU of 3kph by Molmil
Crystal structure of Mycoplasma arthritidis-derived mitogen
Descriptor: PHOSPHATE ION, Superantigen
Authors:Liu, L.H, Li, H.M.
Deposit date:2009-11-16
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Mycoplasma arthritidis-Derived Mitogen in Apo Form Reveals a 3D Domain-Swapped Dimer.
J.Mol.Biol., 399, 2010
7V61
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BU of 7v61 by Molmil
ACE2 -Targeting Monoclonal Antibody as Potent and Broad-Spectrum Coronavirus Blocker
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3E8, ...
Authors:Yan, R.H, Zhang, Y.Y, Li, Y.N, Zhou, Q.
Deposit date:2021-08-18
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker.
Signal Transduct Target Ther, 6, 2021
4HUN
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BU of 4hun by Molmil
MATE transporter NorM-NG in complex with R6G and monobody
Descriptor: Multidrug efflux protein, RHODAMINE 6G, protein B
Authors:Lu, M.
Deposit date:2012-11-02
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HPT
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BU of 4hpt by Molmil
Crystal structure of the catalytic subunit of cAMP-dependent protein kinase displaying complete phosphoryl transfer of AMP-PNP onto a substrate peptide
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Bastidas, A.C, Steichen, J.M, Wu, J, Taylor, S.S.
Deposit date:2012-10-24
Release date:2013-03-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Phosphoryl transfer by protein kinase a is captured in a crystal lattice.
J.Am.Chem.Soc., 135, 2013
4HPU
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BU of 4hpu by Molmil
Crystal structure of the catalytic subunit of cAMP-dependent protein kinase displaying partial phosphoryl transfer of AMP-PNP onto a substrate peptide
Descriptor: MAGNESIUM ION, MYRISTIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Bastidas, A.C, Steichen, J.M, Wu, J, Taylor, S.S.
Deposit date:2012-10-24
Release date:2013-03-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Phosphoryl transfer by protein kinase a is captured in a crystal lattice.
J.Am.Chem.Soc., 135, 2013
4HUL
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BU of 4hul by Molmil
MATE transporter NorM-NG in complex with Cs+ and monobody
Descriptor: CESIUM ION, Multidrug efflux protein, Protein B
Authors:Lu, M.
Deposit date:2012-11-02
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.81 Å)
Cite:Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HUK
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BU of 4huk by Molmil
MATE transporter NorM-NG in complex with TPP and monobody
Descriptor: Multidrug efflux protein, Protein B, TETRAPHENYLPHOSPHONIUM
Authors:Lu, M.
Deposit date:2012-11-02
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HUM
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BU of 4hum by Molmil
MATE transporter NorM-NG in complex with ethidium and monobody
Descriptor: ETHIDIUM, Multidrug efflux protein, Protein B
Authors:Lu, M.
Deposit date:2012-11-02
Release date:2013-02-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.
Proc.Natl.Acad.Sci.USA, 110, 2013

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