7V0E

Crystal structure of the macro-oligomeric form of DNMT3B methyltransferase domain.

Summary for 7V0E

• Entry DOI: 10.2210/pdb7v0e/pdb
• Descriptor: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• Functional Keywords: dnmt3b, dna methylation, methyltransferase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 8
• Total formula weight: 263328.29

Authors

Gao, L.,Lu, J.,Song, J. (deposition date: 2022-05-10, release date: 2022-06-22, Last modification date: 2023-10-18)

• Primary citation: Gao, L.,Guo, Y.,Biswal, M.,Lu, J.,Yin, J.,Fang, J.,Chen, X.,Shao, Z.,Huang, M.,Wang, Y.,Wang, G.G.,Song, J.; Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations.; Nat Commun, 13:4249-4249, 2022; PubMed: 35869095; DOI: 10.1038/s41467-022-31933-w

Experimental method

X-RAY DIFFRACTION (3.27016388184 Å)