7LQW
Cryo-EM structure of NTD-directed neutralizing antibody 2-17 Fab in complex with SARS-CoV-2 S2P spike
Summary for 7LQW
Entry DOI | 10.2210/pdb7lqw/pdb |
EMDB information | 23489 23490 |
Descriptor | 2-17 Heavy Chain, 2-17 Light Chain, Spike glycoprotein, ... (4 entities in total) |
Functional Keywords | covid, covid19, sars-cov2, prefusion, neutralizing, ntd, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 485840.97 |
Authors | Gorman, J.,Rapp, M.,Kwong, P.D.,Shapiro, L. (deposition date: 2021-02-15, release date: 2021-03-24, Last modification date: 2021-05-26) |
Primary citation | Cerutti, G.,Guo, Y.,Zhou, T.,Gorman, J.,Lee, M.,Rapp, M.,Reddem, E.R.,Yu, J.,Bahna, F.,Bimela, J.,Huang, Y.,Katsamba, P.S.,Liu, L.,Nair, M.S.,Rawi, R.,Olia, A.S.,Wang, P.,Zhang, B.,Chuang, G.Y.,Ho, D.D.,Sheng, Z.,Kwong, P.D.,Shapiro, L. Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe, 29:819-833.e7, 2021 Cited by PubMed: 33789084DOI: 10.1016/j.chom.2021.03.005 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.47 Å) |
Structure validation
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