7LMM
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2
Summary for 7LMM
Entry DOI | 10.2210/pdb7lmm/pdb |
Related | 7LMK |
Descriptor | DNA (cytosine-5)-methyltransferase 1,DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION, ... (4 entities in total) |
Functional Keywords | dna methylation, dna methyltransferase 1, histone modification, allosteric regulation, transferase |
Biological source | Bos taurus (Bovine) More |
Total number of polymer chains | 8 |
Total formula weight | 77932.81 |
Authors | |
Primary citation | Ren, W.,Fan, H.,Grimm, S.A.,Kim, J.J.,Li, L.,Guo, Y.,Petell, C.J.,Tan, X.F.,Zhang, Z.M.,Coan, J.P.,Yin, J.,Kim, D.I.,Gao, L.,Cai, L.,Khudaverdyan, N.,Cetin, B.,Patel, D.J.,Wang, Y.,Cui, Q.,Strahl, B.D.,Gozani, O.,Miller, K.M.,O'Leary, S.E.,Wade, P.A.,Wang, G.G.,Song, J. DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation. Nat Commun, 12:2490-2490, 2021 Cited by PubMed: 33941775DOI: 10.1038/s41467-021-22665-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.798 Å) |
Structure validation
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