7LMM

Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	DNA (cytosine-5)-methyltransferase 1,DNA (cytosine-5)-methyltransferase 1	polymer	158	17771.9	4	UniProt (Q24K09) Pfam (PF01426)	Bos taurus (Bovine)	Dnmt1,Dnmt1
2	E, F, G, H (F, G, I, H)	Histone H4	polymer	13	1645.9	4	UniProt (P62805)	Homo sapiens
3	I, J, K, L (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4	M, N, O, P, Q... (A, B, C, D, F...)	water	water		18.0	36	Chemie (HOH)

Sequence modifications

A, B, C, D: 725 - 837 (UniProt: Q24K09)

PDB	External Database	Details
Ser 724	-	expression tag

A, B, C, D: 859 - 897 (UniProt: Q24K09)

PDB	External Database	Details
Gly 838	-	linker
Ala 839	-	linker
Gly 840	-	linker
Ser 841	-	linker
Ala 842	-	linker

F, G, I, H: 14 - 26 (UniProt: P62805)

PDB	External Database	Details
Tyr 26	Ile 27	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	77671.2
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	77932.8

*Water molecules are not included.