7LQV
Cryo-EM structure of NTD-directed neutralizing antibody 4-8 Fab in complex with SARS-CoV-2 S2P spike
Summary for 7LQV
Entry DOI | 10.2210/pdb7lqv/pdb |
EMDB information | 23489 23490 |
Descriptor | Spike glycoprotein, 4-8 Heavy Chain, 4-8 Light chain, ... (4 entities in total) |
Functional Keywords | covid, covid19, sars-cov2, prefusion, neutralizing, ntd, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 9 |
Total formula weight | 512635.48 |
Authors | |
Primary citation | Cerutti, G.,Guo, Y.,ZHou, T.,Gorman, J.,Lee, M.,Rapp, M.,Reddem, E.R.,Yu, J.,Bahna, F.,Bimela, J.,Huang, Y.,Katsamba, PS.,Liu, L.,Nair, M.S.,Rawi, R.,Olia, A.S.,Wang, P.,Zhang, B.,Chuang, G.Y.,Ho, D.D.,Sheng, Z.,Kwong, P.D.,Shapiro, L. Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite Cell Host Microbe, 2021 Cited by DOI: 10.1016/j.chom.2021.03.005PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.25 Å) |
Structure validation
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