7V61

ACE2 -Targeting Monoclonal Antibody as Potent and Broad-Spectrum Coronavirus Blocker

Summary for 7V61

• Entry DOI: 10.2210/pdb7v61/pdb
• EMDB information: 31732
• Descriptor: Sodium-dependent neutral amino acid transporter B(0)AT1, Angiotensin-converting enzyme 2, 3E8, ... (8 entities in total)
• Functional Keywords: ace2-b0at1 complex, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 489753.78

Authors

Yan, R.H.,Zhang, Y.Y.,Li, Y.N.,Zhou, Q. (deposition date: 2021-08-18, release date: 2022-06-22)

• Primary citation: Chen, Y.,Zhang, Y.N.,Yan, R.,Wang, G.,Zhang, Y.,Zhang, Z.R.,Li, Y.,Ou, J.,Chu, W.,Liang, Z.,Wang, Y.,Chen, Y.L.,Chen, G.,Wang, Q.,Zhou, Q.,Zhang, B.,Wang, C.; ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker.; Signal Transduct Target Ther, 6:315-315, 2021; PubMed: 34433803; DOI: 10.1038/s41392-021-00740-y

Experimental method

ELECTRON MICROSCOPY (3.2 Å)