4HPT
Crystal structure of the catalytic subunit of cAMP-dependent protein kinase displaying complete phosphoryl transfer of AMP-PNP onto a substrate peptide
Summary for 4HPT
Entry DOI | 10.2210/pdb4hpt/pdb |
Related | 1ATP 1JBP 1JLU 1L3R 4DFX 4DG0 4DH1 4hpu |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total) |
Functional Keywords | protein kinase, phosphotransferase, regulatory subunits, pki, magnesium, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Mus musculus (mouse) More |
Cellular location | Cytoplasm . Isoform 2: Cell projection, cilium, flagellum : P05132 |
Total number of polymer chains | 2 |
Total formula weight | 43491.49 |
Authors | Bastidas, A.C.,Steichen, J.M.,Wu, J.,Taylor, S.S. (deposition date: 2012-10-24, release date: 2013-03-20, Last modification date: 2017-11-15) |
Primary citation | Bastidas, A.C.,Deal, M.S.,Steichen, J.M.,Guo, Y.,Wu, J.,Taylor, S.S. Phosphoryl transfer by protein kinase a is captured in a crystal lattice. J.Am.Chem.Soc., 135:4788-4798, 2013 Cited by PubMed: 23458248DOI: 10.1021/ja312237q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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