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6BKT
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BU of 6bkt by Molmil
Crystal structure of the A/Michigan/15/2014 (H3N2) influenza virus hemagglutinin in complex with 6'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-11-09
Release date:2018-02-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.
Nat Commun, 9, 2018
4NZT
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BU of 4nzt by Molmil
Crystal structure of the antibody-binding region of Protein M (Protein M TD) in complex with anti-infleunza hemagglutinin antibody CR9114 Fab
Descriptor: CR9114 heavy chain, CR9114 light chain, Protein M TD
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-12-12
Release date:2014-02-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.
Science, 343, 2014
4NM8
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BU of 4nm8 by Molmil
Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8043, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.0041 Å)
Cite:A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NM4
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BU of 4nm4 by Molmil
Crystal structure of broadly neutralizing antibody CR8043
Descriptor: Antibody CR8043, Heavy Chain, Light Chain, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NUJ
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BU of 4nuj by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody PGT152
Descriptor: PGT152 heavy chain, PGT152 light chain
Authors:Blattner, C, Wilson, I.A.
Deposit date:2013-12-03
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.827 Å)
Cite:Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40, 2014
4NZU
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BU of 4nzu by Molmil
Crystal structure of the primary monoclonal antibody 13PL Fab' from a multiple myeloma patient
Descriptor: 13PL heavy chain, 13PL light chain, ACETATE ION, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-12-12
Release date:2014-02-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.
Science, 343, 2014
6CFG
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BU of 6cfg by Molmil
Crystal structure of the A/Vietnam/1203/2004 (H5N1) influenza virus hemagglutinin in complex with small molecule JNJ4796
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Kadam, R.U, Wilson, I.A.
Deposit date:2018-02-14
Release date:2019-02-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:A small-molecule fusion inhibitor of influenza virus is orally active in mice.
Science, 363, 2019
4O58
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BU of 4o58 by Molmil
Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/3/1975 (H3N2) influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-12-19
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7501 Å)
Cite:Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
6CF7
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BU of 6cf7 by Molmil
Crystal structure of the A/Solomon Islands/3/2006(H1N1) influenza virus hemagglutinin in complex with small molecule JNJ4796
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Kadam, R.U, Wilson, I.A.
Deposit date:2018-02-13
Release date:2019-02-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.719 Å)
Cite:A small-molecule fusion inhibitor of influenza virus is orally active in mice.
Science, 363, 2019
6D0U
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BU of 6d0u by Molmil
Crystal structure of C05 V110P/A117E mutant bound to H3 influenza hemagglutinin, HA1 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05 V110P/A117E mutant, heavy chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2018-04-11
Release date:2019-01-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6CXL
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BU of 6cxl by Molmil
anti-HIV-1 Fab 2G12 in complex with glycopeptide 10F5
Descriptor: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, anti-HIV-1 Fab 2G12 heavy chain, anti-HIV-1 Fab 2G12 light chain
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2018-04-03
Release date:2019-02-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.586 Å)
Cite:Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.
ACS Cent Sci, 5, 2019
6D2P
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BU of 6d2p by Molmil
Crystal structure of IOMA-class CLK31 Fab from an HIV-1 naive donor in complex with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.6 A
Descriptor: GLYCEROL, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, IOMAclass naive CLK31 Fab heavy chain, ...
Authors:Sarkar, A, Wilson, I.A.
Deposit date:2018-04-13
Release date:2019-01-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen.
Sci Transl Med, 10, 2018
4NWU
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BU of 4nwu by Molmil
Crystal structure of APE1551, an anti-human NGF Fab with a nine amino acid insertion in CDR H1
Descriptor: APE1551 Ab Fab heavy chain, APE1551 Ab Fab light chain
Authors:Verdino, P, Stanfield, R.L, Wilson, I.A.
Deposit date:2013-12-06
Release date:2014-10-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.
J.Biol.Chem., 289, 2014
4NZR
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BU of 4nzr by Molmil
Crystal structure of the antibody-binding region of Protein M (Protein M TD) in complex with anti-HIV antibody PGT135 Fab
Descriptor: GLYCEROL, PGT135 heavy chain, PGT135 light chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-12-12
Release date:2014-02-19
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.
Science, 343, 2014
4NGH
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BU of 4ngh by Molmil
Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41 and a tethered phosphate moiety.
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41)
Authors:Irimia, A, Wilson, I.A.
Deposit date:2013-11-01
Release date:2014-12-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
Nat.Struct.Mol.Biol., 21, 2014
4NJ9
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BU of 4nj9 by Molmil
Crystal structure of Fab 8B10 in complex with MPTS
Descriptor: 8-methoxypyrene-1,3,6-trisulfonic acid, 8B10 heavy chain, 8B10 light chain, ...
Authors:Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
Deposit date:2013-11-08
Release date:2014-11-12
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
6CA9
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BU of 6ca9 by Molmil
Crystal structure of Fab PCT64_LMCA (SAR), the least mutated common ancestor of the HIV-1 broadly neutralizing antibody lineage PCT64
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, PCT64_LMCA Fab heavy chain, ...
Authors:Omorodion, O, Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
4NCO
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BU of 4nco by Molmil
Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP gp120, BG505 SOSIP gp41, ...
Authors:Julien, J.-P, Stanfield, R.L, Lyumkis, D, Ward, A.B, Wilson, I.A.
Deposit date:2013-10-24
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.7 Å)
Cite:Crystal structure of a soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
6CA7
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BU of 6ca7 by Molmil
Crystal structure of PCT64_13C, a strain specific anti-HIV antibody
Descriptor: PCT64_13C heavy chain, PCT64_13C light chain
Authors:Murrell, S, Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.643 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
4NPY
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BU of 4npy by Molmil
Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: GLYCEROL, germline PGT121 heavy chain, germline PGT121 light chain
Authors:Julien, J.-P, Diwanji, D.C, Wilson, I.A.
Deposit date:2013-11-22
Release date:2013-12-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.
Plos Pathog., 9, 2013
6CA6
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BU of 6ca6 by Molmil
Crystal structure of PCT64_35S, a broadly neutralizing anti-HIV antibody.
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, PCT64_35S heavy chain, ...
Authors:Murrell, S, Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6BKP
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BU of 6bkp by Molmil
Crystal structure of the A/Michigan/15/2014 (H3N2) influenza virus hemagglutinin apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-11-09
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.
Nat Commun, 9, 2018
4O5N
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BU of 4o5n by Molmil
Crystal structure of A/Victoria/361/2011 (H3N2) influenza virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-12-19
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4NWT
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BU of 4nwt by Molmil
Crystal structure of the anti-human NGF Fab APE1531
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, APE1531 Ab Fab heavy chain, ...
Authors:Verdino, P, Stanfield, R.L, Wilson, I.A.
Deposit date:2013-12-06
Release date:2014-10-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.
J.Biol.Chem., 289, 2014
4N60
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BU of 4n60 by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2013-10-11
Release date:2013-12-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9032 Å)
Cite:Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013

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PDB entries from 2024-11-06

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