4NUJ
Crystal structure of HIV-1 broadly neutralizing antibody PGT152
Summary for 4NUJ
Entry DOI | 10.2210/pdb4nuj/pdb |
Descriptor | PGT152 light chain, PGT152 heavy chain (3 entities in total) |
Functional Keywords | immunoglobulin, fab fragment, immune system, hiv envelope |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 50078.11 |
Authors | Blattner, C.,Wilson, I.A. (deposition date: 2013-12-03, release date: 2014-05-14, Last modification date: 2023-09-20) |
Primary citation | Blattner, C.,Lee, J.H.,Sliepen, K.,Derking, R.,Falkowska, E.,de la Pena, A.T.,Cupo, A.,Julien, J.P.,van Gils, M.,Lee, P.S.,Peng, W.,Paulson, J.C.,Poignard, P.,Burton, D.R.,Moore, J.P.,Sanders, R.W.,Wilson, I.A.,Ward, A.B. Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers. Immunity, 40:669-680, 2014 Cited by PubMed: 24768348DOI: 10.1016/j.immuni.2014.04.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.827 Å) |
Structure validation
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