4O58
Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/3/1975 (H3N2) influenza hemagglutinin
Summary for 4O58
Entry DOI | 10.2210/pdb4o58/pdb |
Descriptor | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, Fab F045-092 light chain, ... (10 entities in total) |
Functional Keywords | immunoglobulin, virus attachment and entry, immune recognition, viral protein-immune system complex, viral protein/immune system |
Biological source | Influenza A virus More |
Cellular location | Virion membrane ; Single-pass type I membrane protein : P03435 P03435 |
Total number of polymer chains | 4 |
Total formula weight | 107891.14 |
Authors | Lee, P.S.,Wilson, I.A. (deposition date: 2013-12-19, release date: 2014-04-16, Last modification date: 2023-09-20) |
Primary citation | Lee, P.S.,Ohshima, N.,Stanfield, R.L.,Yu, W.,Iba, Y.,Okuno, Y.,Kurosawa, Y.,Wilson, I.A. Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5:3614-3614, 2014 Cited by PubMed: 24717798DOI: 10.1038/ncomms4614 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7501 Å) |
Structure validation
Download full validation report