6D0U

Crystal structure of C05 V110P/A117E mutant bound to H3 influenza hemagglutinin, HA1 subunit

Summary for 6D0U

Entry DOI	10.2210/pdb6d0u/pdb
Descriptor	Hemagglutinin, Antibody C05 V110P/A117E mutant, heavy chain, Antibody C05, light chain, ... (4 entities in total)
Functional Keywords	computational design, antibody, influenza, hemagglutinin, antiviral protein
Biological source	Influenza A virus More
Total number of polymer chains	12
Total formula weight	320980.15
Authors	Wu, N.C.,Wilson, I.A. (deposition date: 2018-04-11, release date: 2019-01-16, Last modification date: 2023-10-04)
Primary citation	Sevy, A.M.,Wu, N.C.,Gilchuk, I.M.,Parrish, E.H.,Burger, S.,Yousif, D.,Nagel, M.B.M.,Schey, K.L.,Wilson, I.A.,Crowe Jr., J.E.,Meiler, J. Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proc. Natl. Acad. Sci. U.S.A., 116:1597-1602, 2019 Cited by PubMed: 30642961 DOI: 10.1073/pnas.1806004116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.25 Å)

Structure validation