6CA9

Crystal structure of Fab PCT64_LMCA (SAR), the least mutated common ancestor of the HIV-1 broadly neutralizing antibody lineage PCT64

Summary for 6CA9

Entry DOI	10.2210/pdb6ca9/pdb
Related	5FEH 6AC6 6AC7
Descriptor	PCT64_LMCA Fab light chain, PCT64_LMCA Fab heavy chain, GLYCEROL, ... (5 entities in total)
Functional Keywords	igg1, antibody, hiv-1, bnab, immune system
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	98221.03
Authors	Omorodion, O.,Wilson, I.A. (deposition date: 2018-01-29, release date: 2018-06-27, Last modification date: 2023-11-15)
Primary citation	Rantalainen, K.,Berndsen, Z.T.,Murrell, S.,Cao, L.,Omorodion, O.,Torres, J.L.,Wu, M.,Umotoy, J.,Copps, J.,Poignard, P.,Landais, E.,Paulson, J.C.,Wilson, I.A.,Ward, A.B. Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design. Cell Rep, 23:3249-3261, 2018 Cited by PubMed: 29898396 DOI: 10.1016/j.celrep.2018.05.046 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.702 Å)

Structure validation