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4HAC
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BU of 4hac by Molmil
Crystal Structure of the Mevalonate Kinase from an Archaeon Methanosarcina mazei
Descriptor: MAGNESIUM ION, Mevalonate kinase
Authors:Zhuang, N, Lee, K.H.
Deposit date:2012-09-26
Release date:2012-12-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystallization and preliminary X-ray diffraction analysis of mevalonate kinase from Methanosarcina mazei.
Acta Crystallogr.,Sect.F, 68, 2012
3EBJ
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BU of 3ebj by Molmil
Crystal structure of an avian influenza virus protein
Descriptor: MAGNESIUM ION, Polymerase acidic protein
Authors:Yuan, P, Bartlam, M, Lou, Z, Chen, S, Rao, Z, Liu, Y.
Deposit date:2008-08-27
Release date:2009-02-10
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
Nature, 458, 2009
6ISQ
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BU of 6isq by Molmil
structure of Lipase mutant with oxided Cys-His-Asp catalytic triad
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ISOPROPYL ALCOHOL, ...
Authors:Cen, Y.X, Zhou, J.H, Wu, Q.
Deposit date:2018-11-18
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.
Nat Commun, 10, 2019
6ISR
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BU of 6isr by Molmil
structure of lipase mutant with Cys-His-Asp catalytic triad
Descriptor: DI(HYDROXYETHYL)ETHER, Lipase B, NICKEL (II) ION, ...
Authors:Cen, Y.X, Zhou, J.H, Wu, Q.
Deposit date:2018-11-18
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.
Nat Commun, 10, 2019
6ISP
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BU of 6isp by Molmil
structure of Candida antarctica Lipase B mutant
Descriptor: CALCIUM ION, Lipase B, N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE
Authors:Cen, Y.X, Zhou, J.H, Wu, Q.
Deposit date:2018-11-18
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.
Nat Commun, 10, 2019
7DUU
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BU of 7duu by Molmil
Crystal structure of HLA molecule with an KIR receptor
Descriptor: Beta-2-microglobulin, Killer cell immunoglobulin-like receptor 2DS2, LEU-ASN-PRO-SER-VAL-ALA-ALA-THR-LEU, ...
Authors:Yang, Y, Yin, L.
Deposit date:2021-01-11
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Activating receptor KIR2DS2 bound to HLA-C1 reveals the novel recognition features of activating receptor.
Immunology, 165, 2022
8F8Y
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BU of 8f8y by Molmil
PHF2 (PHD+JMJ) in Complex with VRK1 N-Terminal Peptide
Descriptor: 1,2-ETHANEDIOL, Lysine-specific demethylase PHF2, SULFATE ION, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2022-11-22
Release date:2023-01-18
Last modified:2023-02-08
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
8F8Z
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BU of 8f8z by Molmil
PHF2 (PHD+JMJ) in Complex with H3 Histone N-Terminal Peptide
Descriptor: 1,2-ETHANEDIOL, H3 N-Terminal Peptide, Lysine-specific demethylase PHF2, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2022-11-22
Release date:2023-01-18
Last modified:2023-02-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
5HCV
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BU of 5hcv by Molmil
Identification of Spirooxindole and Dibenzoxazepine Motifs as Potent Mineralocorticoid Receptor Antagonists
Descriptor: 6-[(~{E})-(3-fluoranyl-6~{H}-benzo[c][1]benzoxepin-11-ylidene)methyl]-4~{H}-1,4-benzoxazin-3-one, CHLORIDE ION, Mineralocorticoid receptor
Authors:Chen, G, McKeever, B.M.
Deposit date:2016-01-04
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists.
Bioorg.Med.Chem., 24, 2016
6LPD
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BU of 6lpd by Molmil
Phascolosoma esculenta
Descriptor: FE (II) ION, FE (III) ION, Ferritin
Authors:Su, X.R, Ming, T.H.
Deposit date:2020-01-09
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural comparison of two ferritins from the marine invertebrate Phascolosoma esculenta.
Febs Open Bio, 11, 2021
6LP5
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BU of 6lp5 by Molmil
Structure of Sinonovacula constricta ferritin
Descriptor: FE (II) ION, FE (III) ION, Ferritin, ...
Authors:Su, X.R, Ming, T.H, Su, C.
Deposit date:2020-01-08
Release date:2020-04-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystallographic characterization of ferritin from Sinonovacula constricta.
Biochem.Biophys.Res.Commun., 524, 2020
6LPE
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BU of 6lpe by Molmil
Phascolosoma esculenta ferritin
Descriptor: Ferritin, MAGNESIUM ION, SULFATE ION
Authors:Su, X.R, Ming, T.H.
Deposit date:2020-01-10
Release date:2021-02-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural comparison of two ferritins from the marine invertebrate Phascolosoma esculenta.
Febs Open Bio, 11, 2021
6MBD
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BU of 6mbd by Molmil
Human Mcl-1 in complex with the designed peptide dM1
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION, dM1
Authors:Jenson, J.M, Keating, A.E.
Deposit date:2018-08-29
Release date:2019-03-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
6MBC
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BU of 6mbc by Molmil
Human Bfl-1 in complex with the designed peptide dF4
Descriptor: Bcl-2-related protein A1, dF4
Authors:Jenson, J.M, Keating, A.E.
Deposit date:2018-08-29
Release date:2019-03-06
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
1ZA6
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BU of 1za6 by Molmil
The structure of an antitumor CH2-domain-deleted humanized antibody
Descriptor: IGG Heavy chain, IGG Light chain
Authors:Larson, S.B, Day, J.S, Glaser, S, Braslawsky, G, McPherson, A.
Deposit date:2005-04-05
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of an Antitumor C(H)2-domain-deleted Humanized Antibody.
J.Mol.Biol., 348, 2005
7E6G
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BU of 7e6g by Molmil
Crystal structure of diguanylate cyclase SiaD in complex with its activator SiaC from Pseudomonas aeruginosa
Descriptor: DUF1987 domain-containing protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Zhou, J.S, Zhang, L, Zhang, L.
Deposit date:2021-02-22
Release date:2021-09-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for diguanylate cyclase activation by its binding partner in Pseudomonas aeruginosa .
Elife, 10, 2021
2OCG
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BU of 2ocg by Molmil
Crystal structure of human valacyclovir hydrolase
Descriptor: GLYCEROL, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Lai, L, Xu, Z, Amidon, G.L.
Deposit date:2006-12-20
Release date:2008-02-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
2ONM
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BU of 2onm by Molmil
Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with NAD+
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aldehyde dehydrogenase, ...
Authors:Larson, H.N, Hurley, T.D.
Deposit date:2007-01-24
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
J.Biol.Chem., 282, 2007
2ONO
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BU of 2ono by Molmil
Arg475Gln Mutant of Mitochondrial Aldehyde Dehydrogenase, apo form, pseudo-merohedrally twinned
Descriptor: Aldehyde dehydrogenase
Authors:Larson, H.N, Hurley, T.D.
Deposit date:2007-01-24
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
J.Biol.Chem., 282, 2007
2ONN
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BU of 2onn by Molmil
Arg475Gln Mutant of Human Mitochondrial Aldehyde Dehydrogenase, Apo form
Descriptor: Aldehyde dehydrogenase
Authors:Larson, H.N, Hurley, T.D.
Deposit date:2007-01-24
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
J.Biol.Chem., 282, 2007
2ONP
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BU of 2onp by Molmil
Arg475Gln Mutant of Human Mitochondrial Aldehyde Dehydrogenase, complexed with NAD+
Descriptor: 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GUANIDINE, ...
Authors:Larson, H.N, Hurley, T.D.
Deposit date:2007-01-24
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
J.Biol.Chem., 282, 2007
2OCI
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BU of 2oci by Molmil
Crystal structure of valacyclovir hydrolase complexed with a product analogue
Descriptor: L-TYROSINAMIDE, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Lai, L, Xu, Z, Amidon, G.L.
Deposit date:2006-12-20
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
2OCK
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BU of 2ock by Molmil
Crystal structure of valacyclovir hydrolase D123N mutant
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, Valacyclovir hydrolase
Authors:Lai, L, Xu, Z, Amidon, G.L.
Deposit date:2006-12-20
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
2OCL
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BU of 2ocl by Molmil
Crystal structure of valacyclovir hydrolase S122A mutant
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, Valacyclovir hydrolase
Authors:Lai, L, Xu, Z, Amidon, G.L.
Deposit date:2006-12-20
Release date:2008-02-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
7YHW
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BU of 7yhw by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.12.1 RBD in complex with human ACE2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F.
Deposit date:2022-07-14
Release date:2023-07-19
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023

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