8OVW
 
 | | Cryo-EM structure of CBF1-CCAN bound topologically to centromeric DNA | | Descriptor: | C0N3 DNA, Centromere-binding protein 1, Inner kinetochore subunit AME1, ... | | Authors: | Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D. | | Deposit date: | 2023-04-26 | | Release date: | 2023-08-09 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
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8OW1
 | | Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | | Descriptor: | C0N3, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... | | Authors: | Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D. | | Deposit date: | 2023-04-26 | | Release date: | 2023-08-09 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
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7DVM
 | | DgkA structure in E.coli lipid bilayer | | Descriptor: | Diacylglycerol kinase | | Authors: | Li, J, Yang, J. | | Deposit date: | 2021-01-13 | | Release date: | 2022-04-13 | | Last modified: | 2023-09-27 | | Method: | SOLID-STATE NMR | | Cite: | Structure of membrane diacylglycerol kinase in lipid bilayers.
Commun Biol, 4, 2021
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8JDN
 | | Crystal structure of H405A mLDHD in complex with D-2-hydroxyvaleric acid | | Descriptor: | (2R)-2-oxidanylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDS
 | | Crystal structure of mLDHD in complex with Pyruvate | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, PYRUVIC ACID, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.636 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDB
 | | Crystal structure of H405A mLDHD in complex with D-2-hydroxyoctanoic acid | | Descriptor: | (2R)-2-oxidanyloctanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-13 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDC
 | | Crystal structure of mLDHD in apo form | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-13 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.696 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDQ
 | | Crystal structure of H405A mLDHD in complex with D-2-hydroxyisocaproic acid | | Descriptor: | (2R)-2-hydroxy-4-methylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDT
 | | Crystal structure of mLDHD in complex with 2-ketobutanoic acid | | Descriptor: | 2-KETOBUTYRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDV
 | | Crystal structure of mLDHD in complex with 2-ketohexanoic acid | | Descriptor: | 2-Ketohexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDG
 | | Crystal structure of H405A mLDHD in complex with D-2-hydroxybutanoic acid | | Descriptor: | (2R)-2-oxidanylbutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-14 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDR
 | | Crystal structure of H405A mLDHD in complex with D-2-hydroxy-3-methyl-valeric acid | | Descriptor: | (2R,3S)-3-methyl-2-oxidanyl-pentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDU
 | | Crystal structure of mLDHD in complex with 2-ketovaleric acid | | Descriptor: | 2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDY
 | | Crystal structure of mLDHD in complex with 2-ketoisocaproic acid | | Descriptor: | 2-OXO-4-METHYLPENTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDD
 | | Crystal structure of H405A mLDHD in apo form | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-13 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDZ
 | | Crystal structure of mLDHD in complex with 2-keto-3-methylvaleric acid | | Descriptor: | (3S)-3-methyl-2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDF
 | | Crystal structure of H405A mLDHD in complex with D-lactate | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, Probable D-lactate dehydrogenase, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-13 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDX
 | | Crystal structure of mLDHD in complex with 2-ketoisovaleric acid | | Descriptor: | 3-METHYL-2-OXOBUTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDE
 | | Crystal structure of mLDHD in complex with D-lactate | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, MANGANESE (II) ION, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-13 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.729 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDO
 | | Crystal structure of H405A mLDHD in complex with D-2-hydroxyhexanoic acid | | Descriptor: | (2R)-2-hydroxyhexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDP
 | | Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid | | Descriptor: | DEAMINOHYDROXYVALINE, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | | Deposit date: | 2023-05-15 | | Release date: | 2023-10-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8I2H
 | | Follicle stimulating hormone receptor | | Descriptor: | Follicle-stimulating hormone receptor | | Authors: | Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E. | | Deposit date: | 2023-01-14 | | Release date: | 2023-03-22 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (6 Å) | | Cite: | Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor.
Nat Commun, 14, 2023
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8I2G
 | | FSHR-Follicle stimulating hormone-compound 716340-Gs complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E. | | Deposit date: | 2023-01-14 | | Release date: | 2023-03-29 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor.
Nat Commun, 14, 2023
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6JUI
 | | The atypical Myb-like protein Cdc5 contains two distinct nucleic acid-binding surfaces | | Descriptor: | Pre-mRNA-splicing factor CEF1 | | Authors: | Wang, C, Li, G, Li, M, Yang, J, Liu, J. | | Deposit date: | 2019-04-14 | | Release date: | 2020-02-19 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.402 Å) | | Cite: | Two distinct nucleic acid binding surfaces of Cdc5 regulate development.
Biochem.J., 476, 2019
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6IGB
 | | the structure of Pseudomonas aeruginosa Periplasmic gluconolactonase, PpgL | | Descriptor: | ACETATE ION, Periplasmic gluconolactonase, PpgL, ... | | Authors: | Song, Y.J, Shen, Y.L, Wang, K.L, Li, T, Zhu, Y.B, Li, C.C, He, L.H, Zhao, N.L, Zhao, C, Yang, J, Huang, Q, Mu, X.Y. | | Deposit date: | 2018-09-25 | | Release date: | 2018-11-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.651 Å) | | Cite: | Structural and Functional Insights into PpgL, a Metal-Independent beta-Propeller Gluconolactonase That Contributes toPseudomonas aeruginosaVirulence.
Infect.Immun., 87, 2019
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