8JDS

Crystal structure of mLDHD in complex with Pyruvate

Summary for 8JDS

• Entry DOI: 10.2210/pdb8jds/pdb
• Descriptor: Probable D-lactate dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... (5 entities in total)
• Functional Keywords: d-lactate dehydrogenase, ldhd, 2-hydroxyacid, oxidoreductase
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 1
• Total formula weight: 51381.41

Authors

Jin, S.,Chen, X.,Yang, J.,Ding, J. (deposition date: 2023-05-15, release date: 2023-10-18, Last modification date: 2024-02-21)

• Primary citation: Jin, S.,Chen, X.,Yang, J.,Ding, J.; Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.; Nat Commun, 14:6638-6638, 2023; PubMed: 37863926; DOI: 10.1038/s41467-023-42456-3

Experimental method

X-RAY DIFFRACTION (1.636 Å)