8OVW

Cryo-EM structure of CBF1-CCAN bound topologically to centromeric DNA

Summary for 8OVW

Entry DOI	10.2210/pdb8ovw/pdb
EMDB information	17224
Descriptor	Centromere-binding protein 1, Inner kinetochore subunit OKP1, Inner kinetochore subunit CNN1, ... (16 entities in total)
Functional Keywords	kinetochore, point centromere, cenp-a nucleosome, topological entrapment, centromeric dna, cell cycle
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Total number of polymer chains	17
Total formula weight	654576.81
Authors	Dendooven, T.D.,Zhang, Z.,Yang, J.,McLaughlin, S.,Schwabb, J.,Scheres, S.,Yatskevich, S.,Barford, D. (deposition date: 2023-04-26, release date: 2023-08-09)
Primary citation	Dendooven, T.,Zhang, Z.,Yang, J.,McLaughlin, S.H.,Schwab, J.,Scheres, S.H.W.,Yatskevich, S.,Barford, D. Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere. Sci Adv, 9:eadg7480-eadg7480, 2023 Cited by PubMed: 37506202 DOI: 10.1126/sciadv.adg7480 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation