5WTJ
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![BU of 5wtj by Molmil](/molmil-images/mine/5wtj) | Crystal structure of an endonuclease | Descriptor: | CRISPR-associated endoribonuclease C2c2 | Authors: | Liu, L, Wang, Y. | Deposit date: | 2016-12-13 | Release date: | 2017-02-08 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (3.503 Å) | Cite: | Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities Cell, 168, 2017
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7R63
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7R0A
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![BU of 7r0a by Molmil](/molmil-images/mine/7r0a) | Structure of sarin phosphonylated acetylcholinesterase in complex with 2-((hydroxyimino)methyl)-1-(5-(4-methyl-3-nitrobenzamido)pentyl)pyridinium | Descriptor: | 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, 2-(2-METHOXYETHOXY)ETHANOL, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, ... | Authors: | Forsgren, N, Lindgren, C, Edvinsson, L, Linusson, A, Ekstrom, F. | Deposit date: | 2022-02-01 | Release date: | 2022-04-27 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Broad-Spectrum Antidote Discovery by Untangling the Reactivation Mechanism of Nerve-Agent-Inhibited Acetylcholinesterase. Chemistry, 28, 2022
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1ZGH
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![BU of 1zgh by Molmil](/molmil-images/mine/1zgh) | Methionyl-tRNA formyltransferase from Clostridium thermocellum | Descriptor: | Methionyl-tRNA formyltransferase, UNKNOWN ATOM OR ION | Authors: | Yang, H, Kataeva, I, Xu, H, Zhao, M, Chang, J, Liu, Z, Chen, L, Tempel, W, Habel, J, Zhou, W, Lee, D, Lin, D, Chang, S, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Wang, B, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2005-04-21 | Release date: | 2005-05-03 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Methionyl-tRNA formyltransferase from Clostridium thermocellum To be published
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1N3J
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![BU of 1n3j by Molmil](/molmil-images/mine/1n3j) | Structure and Substrate of a Histone H3 Lysine Methyltransferase from Paramecium Bursaria Chlorella Virus 1 | Descriptor: | Histone H3 Lysine Methyltransferase | Authors: | Manzur, K.L, Farooq, A, Zeng, L, Plotnikova, O, Sachchidanand, Koch, A.W, Zhou, M.-M. | Deposit date: | 2002-10-28 | Release date: | 2003-01-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3. Nat.Struct.Biol., 10, 2003
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5AYW
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![BU of 5ayw by Molmil](/molmil-images/mine/5ayw) | Structure of a membrane complex | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | Authors: | Huang, Y, Han, L, Zheng, J. | Deposit date: | 2015-09-14 | Release date: | 2016-02-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.555 Å) | Cite: | Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins Nat.Struct.Mol.Biol., 23, 2016
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1ZKP
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![BU of 1zkp by Molmil](/molmil-images/mine/1zkp) | 1.5A Resolution Crystal Structure of a Metallo Beta Lactamase Family Protein, the ELAC Homolgue of Bacillus anthracis, a Putative Ribonuclease | Descriptor: | CHLORIDE ION, SODIUM ION, ZINC ION, ... | Authors: | Brunzelle, J.S, Minasov, G, Shuvalova, L, Collart, F.R, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-05-03 | Release date: | 2005-06-21 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | 1.5A Resolution Crystal Structure of a Metallo Beta Lactamase Family
Protein, the ELAC Homolgue of Bacillus anthracis, a Putative Ribonuclease To be Published
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1ZMO
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![BU of 1zmo by Molmil](/molmil-images/mine/1zmo) | Apo structure of haloalcohol dehalogenase HheA of Arthrobacter sp. AD2 | Descriptor: | halohydrin dehalogenase | Authors: | de Jong, R.M, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2005-05-10 | Release date: | 2006-04-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family. J.Bacteriol., 188, 2006
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5B02
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![BU of 5b02 by Molmil](/molmil-images/mine/5b02) | Structure of the prenyltransferase MoeN5 with a fusion protein tag of Sso7d | Descriptor: | MoeN5,DNA-binding protein 7d | Authors: | Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O. | Deposit date: | 2015-10-27 | Release date: | 2016-03-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5. Angew.Chem.Int.Ed.Engl., 55, 2016
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1N4O
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6HB3
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![BU of 6hb3 by Molmil](/molmil-images/mine/6hb3) | Structure of Hgh1, crystal form II | Descriptor: | Protein HGH1 | Authors: | Moenkemeyer, L, Klaips, C.L, Balchin, D, Koerner, R, Hartl, F.U, Bracher, A. | Deposit date: | 2018-08-09 | Release date: | 2019-02-27 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2. Mol.Cell, 74, 2019
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5BOE
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![BU of 5boe by Molmil](/molmil-images/mine/5boe) | Crystal structure of Staphylococcus aureus enolase in complex with PEP | Descriptor: | Enolase, GLYCEROL, MAGNESIUM ION, ... | Authors: | Wang, C.L, Wu, Y.F, Han, L, Wu, M.H, Zhang, X, Zang, J.Y. | Deposit date: | 2015-05-27 | Release date: | 2015-12-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Octameric structure of Staphylococcus aureus enolase in complex with phosphoenolpyruvate Acta Crystallogr.,Sect.D, 71, 2015
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1ZMZ
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![BU of 1zmz by Molmil](/molmil-images/mine/1zmz) | Solution structure of the N-terminal domain (M1-S98) of human centrin 2 | Descriptor: | Centrin-2 | Authors: | Yang, A, Miron, S, Duchambon, P, Assairi, L, Blouquit, Y, Craescu, C.T. | Deposit date: | 2005-05-11 | Release date: | 2006-04-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The N-terminal domain of human centrin 2 has a closed structure, binds calcium with a very low affinity, and plays a role in the protein self-assembly Biochemistry, 45, 2006
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5M5D
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![BU of 5m5d by Molmil](/molmil-images/mine/5m5d) | Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with mannose-alpha-1,3-D-glucal | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Glycosyl hydrolase family 71, ... | Authors: | Petricevic, M, Sobala, L.F, Fernandes, P.Z, Raich, L, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J. | Deposit date: | 2016-10-21 | Release date: | 2017-01-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.07 Å) | Cite: | Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-alpha-1,2-Mannanase. J. Am. Chem. Soc., 139, 2017
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1NC6
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![BU of 1nc6 by Molmil](/molmil-images/mine/1nc6) | Potent, small molecule inhibitors of human mast cell tryptase. Anti-asthmatic action of a dipeptide-based transition state analogue containing benzothiazole ketone | Descriptor: | (2S,4R)-1-ACETYL-N-[(1S)-4-[(AMINOIMINOMETHYL)AMINO]-1-(2-BENZOTHIAZOLYLCARBONYL)BUTYL]-4-HYDROXY-2-PYRROLIDINECARBOXAMIDE, CALCIUM ION, SULFATE ION, ... | Authors: | Costanzo, M.J, Yabut, S.C, Almond Jr, H.R, Andrade-Gordon, P, Corcoran, T.W, de Garavilla, L, Kauffman, J.A, Abraham, W.M, Recacha, R, Chattopadhyay, D, Maryanoff, B.E. | Deposit date: | 2002-12-04 | Release date: | 2003-09-23 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Potent, Small-Molecule Inhibitors of Human Mast Cell Tryptase. Antiasthmatic Action of a Dipeptide-Based Transition-State Analogue Containing a Benzothiazole Ketone. J.Med.Chem., 46, 2003
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1ND5
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![BU of 1nd5 by Molmil](/molmil-images/mine/1nd5) | Crystal Structures of Human Prostatic Acid Phosphatase in Complex with a Phosphate Ion and alpha-Benzylaminobenzylphosphonic Acid Update the Mechanistic Picture and Offer New Insights into Inhibitor Design | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ortlund, E, LaCount, M.W, Lebioda, L. | Deposit date: | 2002-12-07 | Release date: | 2002-12-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of human prostatic acid phosphatase in complex with a
phosphate ion and alpha-benzylaminobenzylphosphonic acid update the
mechanistic picture and offer new insights into inhibitor design Biochemistry, 42, 2003
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1MU6
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![BU of 1mu6 by Molmil](/molmil-images/mine/1mu6) | Crystal Structure of Thrombin in Complex with L-378,622 | Descriptor: | 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDE, HIRUDIN IIB, THROMBIN | Authors: | Burgey, C.S, Robinson, K.A, Lyle, T.A, Sanderson, P.E, Lewis, S.D, Lucas, B.J, Krueger, J.A, Singh, R, Miller-Stein, C, White, R.B, Wong, B, Lyle, E.A, Williams, P.D, Coburn, C.A, Dorsey, B.D, Barrow, J.C, Stranieri, M.T, Holahan, M.A, Sitko, G.R, Cook, J.J, McMasters, D.R, McDonough, C.M, Sanders, W.M, Wallace, A.A, Clayton, F.C, Bohn, D, Leonard, Y.M, Detwiler Jr, T.J, Lynch Jr, J.J, Yan, Y, Chen, Z, Kuo, L, Gardell, S.J, Shafer, J.A, Vacca, J.P.J. | Deposit date: | 2002-09-23 | Release date: | 2004-04-06 | Last modified: | 2021-07-21 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines. J.Med.Chem., 46, 2003
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5LWC
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![BU of 5lwc by Molmil](/molmil-images/mine/5lwc) | NMR solution structure of bacteriocin BacSp222 from Staphylococcus pseudintermedius 222 | Descriptor: | Bacteriocin BacSp222 | Authors: | Nowakowski, M.E, Ejchart, A.O, Jaremko, L, Wladyka, B, Mak, P. | Deposit date: | 2016-09-15 | Release date: | 2017-10-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Spatial attributes of the four-helix bundle group of bacteriocins - The high-resolution structure of BacSp222 in solution. Int.J.Biol.Macromol., 107, 2018
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1YZ6
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5WYM
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![BU of 5wym by Molmil](/molmil-images/mine/5wym) | Crystal structure of an anti-connexin26 scFv | Descriptor: | anti-connexin26 scFv,Ig heavy chain,Linker,anti-connexin26 scFv,Ig light chain | Authors: | Li, S, Xu, L. | Deposit date: | 2017-01-13 | Release date: | 2018-01-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders Front Mol Neurosci, 10, 2017
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1YWN
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![BU of 1ywn by Molmil](/molmil-images/mine/1ywn) | Vegfr2 in complex with a novel 4-amino-furo[2,3-d]pyrimidine | Descriptor: | N-{4-[4-AMINO-6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-5-YL]PHENYL}-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA, Vascular endothelial growth factor receptor 2 | Authors: | Miyazaki, Y, Matsunaga, S, Tang, J, Maeda, Y, Nakano, M, Philippe, R.J, Shibahara, M, Liu, W, Sato, H, Wang, L, Nolte, R.T. | Deposit date: | 2005-02-18 | Release date: | 2005-08-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitors Bioorg.Med.Chem.Lett., 15, 2005
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1YX0
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![BU of 1yx0 by Molmil](/molmil-images/mine/1yx0) | Solution Structure of Bacillus subtilis Protein ysnE: The Northeast Structural Genomics Consortium Target SR220 | Descriptor: | hypothetical protein ysnE | Authors: | Liu, G, Ma, L, Shen, Y, Xiao, R, Acton, T, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-02-18 | Release date: | 2005-03-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of Bacillus subtilis Protein ysnE To be Published
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1Z05
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![BU of 1z05 by Molmil](/molmil-images/mine/1z05) | Crystal structure of the ROK family transcriptional regulator, homolog of E.coli MLC protein. | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, SULFATE ION, ... | Authors: | Minasov, G, Brunzelle, J.S, Shuvalova, L, Collart, F.R, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-03-01 | Release date: | 2005-03-08 | Last modified: | 2018-06-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the ROK family transcriptional regulator, homolog of E.coli MLC protein. To be Published
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1NJT
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![BU of 1njt by Molmil](/molmil-images/mine/1njt) | COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR | Descriptor: | CHLORIDE ION, Capsid protein P40, Peptidomimetic Inhibitor | Authors: | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | Deposit date: | 2003-01-02 | Release date: | 2003-02-11 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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5WTK
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![BU of 5wtk by Molmil](/molmil-images/mine/5wtk) | Crystal structure of RNP complex | Descriptor: | CRISPR-associated endoribonuclease C2c2, RNA (58-MER) | Authors: | Liu, L, Wang, Y. | Deposit date: | 2016-12-13 | Release date: | 2017-02-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities Cell, 168, 2017
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