1NJT

COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR

Summary for 1NJT

Related2WPO 1NJU 1NKK 1NKM
Related PRD IDPRD_000405
DescriptorCapsid protein P40, Peptidomimetic Inhibitor, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsprotease, peptidomimetic inhibitor, induced-fit, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHuman herpesvirus 5 (Human cytomegalovirus)
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Cellular locationProtease precursor: Host cytoplasm. Assemblin: Host nucleus. Assembly protein: Host nucleus P16753
Total number of polymer chains8
Total molecular weight114870.23
Authors
Khayat, R.,Batra, R.,Qian, C.,Halmos, T.,Bailey, M.,Tong, L. (deposition date: 2003-01-02, release date: 2003-02-11, Last modification date: 2013-02-27)
Primary citation
Khayat, R.,Batra, R.,Qian, C.,Halmos, T.,Bailey, M.,Tong, L.
Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease
Biochemistry, 42:885-891, 2003
PubMed: 12549906 (PDB entries with the same primary citation)
DOI: 10.1021/bi027045s
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers181.1%8.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
167518
PDB entries from 2020-08-12