1NJU
Complex structure of HCMV Protease and a peptidomimetic inhibitor
Summary for 1NJU
Entry DOI | 10.2210/pdb1nju/pdb |
Related | 1NJT 1NKK 1NKM |
Related PRD ID | PRD_000283 |
Descriptor | Assemblin, N-(6-aminohexanoyl)-3-methyl-L-valyl-3-methyl-L-valyl-N~1~-[(2S,3S)-3-hydroxy-4-oxo-4-{[(1R)-1-phenylpropyl]amino}butan-2-yl]-N~4~,N~4~-dimethyl-L-aspartamide (2 entities in total) |
Functional Keywords | protease, peptidomimetic inhibitor, induced-fit, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human herpesvirus 5 (Human cytomegalovirus) |
Cellular location | Protease precursor: Host cytoplasm. Assemblin: Host nucleus. Assembly protein: Host nucleus: P16753 |
Total number of polymer chains | 4 |
Total formula weight | 115393.94 |
Authors | Khayat, R.,Batra, R.,Qian, C.,Halmos, T.,Bailey, M.,Tong, L. (deposition date: 2003-01-02, release date: 2003-02-11, Last modification date: 2024-03-13) |
Primary citation | Khayat, R.,Batra, R.,Qian, C.,Halmos, T.,Bailey, M.,Tong, L. Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42:885-891, 2003 Cited by PubMed: 12549906DOI: 10.1021/bi027045s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report