1NKK

COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR

Summary for 1NKK

• Entry DOI: 10.2210/pdb1nkk/pdb
• Related: 1NJT 1NJU 1NKM 2WPO
• Related PRD ID: PRD_000405
• Descriptor: Capsid protein P40, Peptidomimetic inhibitor (3 entities in total)
• Functional Keywords: protease, peptidomimetic inhibitor, induced-fit, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human herpesvirus 5 (Human cytomegalovirus); More
• Cellular location: Protease precursor: Host cytoplasm. Assemblin: Host nucleus. Assembly protein: Host nucleus: P16753
• Total number of polymer chains: 8
• Total formula weight: 114840.74

Authors

Khayat, R.,Batra, R.,Qian, C.,Halmos, T.,Bailey, M.,Tong, L. (deposition date: 2003-01-03, release date: 2003-02-11, Last modification date: 2021-10-27)

• Primary citation: Khayat, R.,Batra, R.,Qian, C.,Halmos, T.,Bailey, M.,Tong, L.; Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease; Biochemistry, 42:885-891, 2003; PubMed: 12549906; DOI: 10.1021/bi027045s

Experimental method

X-RAY DIFFRACTION (2.6 Å)