1ND5

Crystal Structures of Human Prostatic Acid Phosphatase in Complex with a Phosphate Ion and alpha-Benzylaminobenzylphosphonic Acid Update the Mechanistic Picture and Offer New Insights into Inhibitor Design

Summary for 1ND5

Entry DOI	10.2210/pdb1nd5/pdb
Related	1CVI 1ND6 2HPA
Descriptor	prostatic acid phosphatase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	acid phosphatase, pap, prostate, phosphate, inhibitor, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	169944.22
Authors	Ortlund, E.,LaCount, M.W.,Lebioda, L. (deposition date: 2002-12-07, release date: 2002-12-20, Last modification date: 2023-08-16)
Primary citation	Ortlund, E.,LaCount, M.W.,Lebioda, L. Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design Biochemistry, 42:383-389, 2003 Cited by PubMed: 12525165 DOI: 10.1021/bi0265067 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation