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5WYM

Crystal structure of an anti-connexin26 scFv

Summary for 5WYM
Entry DOI10.2210/pdb5wym/pdb
Descriptoranti-connexin26 scFv,Ig heavy chain,Linker,anti-connexin26 scFv,Ig light chain (2 entities in total)
Functional Keywordsantibody, scfv, connexin26, immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight50928.68
Authors
Li, S.,Xu, L. (deposition date: 2017-01-13, release date: 2018-01-24, Last modification date: 2023-11-22)
Primary citationXu, L.,Carrer, A.,Zonta, F.,Qu, Z.,Ma, P.,Li, S.,Ceriani, F.,Buratto, D.,Crispino, G.,Zorzi, V.,Ziraldo, G.,Bruno, F.,Nardin, C.,Peres, C.,Mazzarda, F.,Salvatore, A.M.,Raspa, M.,Scavizzi, F.,Chu, Y.,Xie, S.,Yang, X.,Liao, J.,Liu, X.,Wang, W.,Wang, S.,Yang, G.,Lerner, R.A.,Mammano, F.
Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders
Front Mol Neurosci, 10:298-298, 2017
Cited by
PubMed: 29018324
DOI: 10.3389/fnmol.2017.00298
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.65 Å)
Structure validation

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