3J94
 
 | | Structure of ATP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Vesicle-fusing ATPase | | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | Deposit date: | 2014-12-05 | | Release date: | 2015-01-28 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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8U30
 | | TRPV1 in nanodisc bound with diC8-PIP2 in the closed state | | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily V member 1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | Authors: | Arnold, W.R, Julius, D, Cheng, Y. | | Deposit date: | 2023-09-06 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
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8U3L
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8U2Z
 | | TRPV1 in nanodisc bound with diC8-PIP2 in the dilated state | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, SODIUM ION, ... | | Authors: | Arnold, W.R, Julius, D, Cheng, Y. | | Deposit date: | 2023-09-06 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
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8U3C
 | | TRPV1 in nanodisc bound with PI-Br4 bound in Conformation 2 (monomer) | | Descriptor: | (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | Authors: | Arnold, W.R, Julius, D, Cheng, Y. | | Deposit date: | 2023-09-07 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
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8U3A
 | | TRPV1 in nanodisc bound with PI-Br4 bound in Conformation 1 (monomer) | | Descriptor: | (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SODIUM ION, ... | | Authors: | Arnold, W.R, Julius, D, Cheng, Y. | | Deposit date: | 2023-09-07 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
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8U3J
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8U43
 | | TRPV1 in nanodisc bound with PIP2-Br4 | | Descriptor: | (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SODIUM ION, ... | | Authors: | Arnold, W.R, Julius, D, Cheng, Y. | | Deposit date: | 2023-09-08 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
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8U4D
 | | TRPV1 in nanodisc bound with PI-Br4, consensus structure | | Descriptor: | (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1 | | Authors: | Arnold, W.R, Julius, D, Cheng, Y. | | Deposit date: | 2023-09-10 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Structural basis of TRPV1 modulation by endogenous bioactive lipids.
Nat.Struct.Mol.Biol., 2024
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2B34
 | | Structure of MAR1 Ribonuclease from Caenorhabditis elegans | | Descriptor: | MAR1 Ribonuclease | | Authors: | Schormann, N, Karpova, E, Li, S, Symersky, J, Zhang, Y, Lu, S, Zhou, Q, Lin, G, Cao, Z, Luo, M, Qiu, S, Luan, C.-H, Luo, D, Huang, W, Shang, Q, McKinstry, A, An, J, Tsao, J, Carson, M, Stinnett, M, Chen, Y, Johnson, D, Gary, R, Arabshahi, A, Bunzel, R, Bray, T, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2005-09-19 | | Release date: | 2005-09-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.141 Å) | | Cite: | Structure of MAR1 Ribonuclease from Caenorhabditis elegans
To be Published
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4ERG
 | | Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase | | Descriptor: | 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, FE (III) ION | | Authors: | Huo, L, Fielding, A.J, Chen, Y, Li, T, Iwaki, H, Hosler, J.P, Chen, L, Hasegawa, Y, Que Jr, L, Liu, A. | | Deposit date: | 2012-04-20 | | Release date: | 2012-08-22 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.789 Å) | | Cite: | Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase
Biochemistry, 51, 2012
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4GM3
 | | Crystal structure of human WD repeat domain 5 with compound MM-101 | | Descriptor: | MM-101, WD repeat-containing protein 5 | | Authors: | Karatas, H, Townsend, E.C, Chen, Y, Bernard, D, Cao, F, Liu, L, Lei, M, Dou, Y, Wang, S. | | Deposit date: | 2012-08-15 | | Release date: | 2013-07-31 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.393 Å) | | Cite: | High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction.
J.Am.Chem.Soc., 135, 2013
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4GP4
 | | Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133F from Thermus thermophilus | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, ... | | Authors: | Li, Y, Chen, Y, Stout, C.D. | | Deposit date: | 2012-08-20 | | Release date: | 2013-01-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Ligand Access to the Active Site in Thermus thermophilusba(3) and Bovine Heart aa(3) Cytochrome Oxidases.
Biochemistry, 52, 2013
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3C5W
 | | Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme | | Descriptor: | PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1 | | Authors: | Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. | | Deposit date: | 2008-02-01 | | Release date: | 2008-04-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural mechanism of demethylation and inactivation of protein phosphatase 2A.
Cell(Cambridge,Mass.), 133, 2008
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3J5R
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3J2B
 | | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | | Descriptor: | 16S rRNA | | Authors: | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | | Deposit date: | 2012-09-28 | | Release date: | 2013-01-16 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (13.6 Å) | | Cite: | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process
Nucleic Acids Res., 41, 2013
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4IWG
 | | Crystal Structure of the Conserved Hypothetical Protein MJ0927 from Methanocaldococcus jannaschii (in C2221 form) | | Descriptor: | UPF0135 protein MJ0927 | | Authors: | Kuan, S.M, Chen, S.C, Yang, C.S, Chen, Y.R, Liu, Y.H, Chen, Y. | | Deposit date: | 2013-01-23 | | Release date: | 2014-01-29 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.472 Å) | | Cite: | Crystal structure of a conserved hypothetical protein MJ0927 from Methanocaldococcus jannaschii reveals a novel quaternary assembly in the Nif3 family.
Biomed Res Int, 2014, 2014
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5A9Y
 | | Structure of ppGpp BipA | | Descriptor: | GTP-BINDING PROTEIN, GUANOSINE-5',3'-TETRAPHOSPHATE | | Authors: | Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G. | | Deposit date: | 2015-07-23 | | Release date: | 2015-08-26 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
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7W6L
 | | The crystal structure of MLL3-RBBP5-ASH2L in complex with H3K4me0 peptide | | Descriptor: | Histone H3.3C, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ... | | Authors: | Zhao, L, Li, Y, Chen, Y. | | Deposit date: | 2021-12-01 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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7W6A
 | | Crystal structure of the MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L complex | | Descriptor: | Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Zhao, L, Li, Y, Chen, Y. | | Deposit date: | 2021-12-01 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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7W6I
 | | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me1 peptide | | Descriptor: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | | Authors: | Zhao, L, Li, Y, Chen, Y. | | Deposit date: | 2021-12-01 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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6IF8
 | | Aeromonas hydrophila MtaN-2 complexed with adenine | | Descriptor: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE | | Authors: | Chen, J, Liu, W, Wang, L, Shang, F, Lan, J, Chen, Y, Xu, Y. | | Deposit date: | 2018-09-18 | | Release date: | 2018-10-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Aeromonas hydrophila MtaN-2 complexed with adenine
To Be Published
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7W67
 | | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me0 peptide | | Descriptor: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | | Authors: | Zhao, L, Li, Y, Chen, Y. | | Deposit date: | 2021-12-01 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.194 Å) | | Cite: | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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7W6J
 | | The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me2 peptide | | Descriptor: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | | Authors: | Zhao, L, Li, Y, Chen, Y. | | Deposit date: | 2021-12-01 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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4IXA
 | | Structure of DNA-binding domain of the response regulator SaeR from Staphylococcus epidermidis | | Descriptor: | Response regulator SaeR | | Authors: | Chen, Y.R, Chen, S.C, Yang, C.S, Kuan, S.M, Liu, Y.H, Chen, Y. | | Deposit date: | 2013-01-24 | | Release date: | 2014-01-29 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure of DNA-binding domain of the response regulator SaeR from Staphylococcus epidermidis
To be Published
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