8U4D
TRPV1 in nanodisc bound with PI-Br4, consensus structure
Summary for 8U4D
Entry DOI | 10.2210/pdb8u4d/pdb |
EMDB information | 41879 |
Descriptor | Transient receptor potential cation channel subfamily V member 1, (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate, SODIUM ION, ... (4 entities in total) |
Functional Keywords | trpv1 in nanodisc bound with pi-br4, consensus structure membrane protein, membrane protein |
Biological source | Rattus norvegicus (Norway rat) |
Total number of polymer chains | 4 |
Total formula weight | 296306.79 |
Authors | Arnold, W.R.,Julius, D.,Cheng, Y. (deposition date: 2023-09-10, release date: 2024-05-08, Last modification date: 2024-05-15) |
Primary citation | Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y. Structural basis of TRPV1 modulation by endogenous bioactive lipids. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38698206DOI: 10.1038/s41594-024-01299-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.2 Å) |
Structure validation
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