8U3C

TRPV1 in nanodisc bound with PI-Br4 bound in Conformation 2 (monomer)

Summary for 8U3C

Entry DOI	10.2210/pdb8u3c/pdb
EMDB information	41857
Descriptor	Transient receptor potential cation channel subfamily V member 1, (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (6 entities in total)
Functional Keywords	trpv1 in nanodisc bound with pi-br4 bound in conformation 2 (monomer), membrane protein
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	2
Total formula weight	188006.18
Authors	Arnold, W.R.,Julius, D.,Cheng, Y. (deposition date: 2023-09-07, release date: 2024-05-08, Last modification date: 2024-05-15)
Primary citation	Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y. Structural basis of TRPV1 modulation by endogenous bioactive lipids. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38698206 DOI: 10.1038/s41594-024-01299-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.3 Å)

Structure validation