8U3C

TRPV1 in nanodisc bound with PI-Br4 bound in Conformation 2 (monomer)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Transient receptor potential cation channel subfamily V member 1	polymer	815	92654.2	2	UniProt (O35433) Pfam (PF00023) Pfam (PF00520) In PDB	Rattus norvegicus (Norway rat)	TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like
2	A	(2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate	non-polymer		1182.7	1	Chemie (VPN)
3	A	1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		787.1	1	Chemie (PCW)
4	A	1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE	non-polymer		705.0	1	Chemie (3PH)
5	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6		water	water		18.0	12	Chemie (HOH)

Sequence modifications

A, D: 1 - 838 (UniProt: O35433)

PDB	External Database	Details
-	Asn 604	deletion
-	Asn 605	deletion
-	Ser 606	deletion
-	Leu 607	deletion
-	Pro 608	deletion
-	Met 609	deletion
-	Glu 610	deletion
-	Ser 611	deletion
-	Thr 612	deletion
-	Pro 613	deletion
-	His 614	deletion
-	Lys 615	deletion
-	Cys 616	deletion
-	Arg 617	deletion
-	Gly 618	deletion
-	Ser 619	deletion
-	Ala 620	deletion
-	Cys 621	deletion
-	Lys 622	deletion
-	Pro 623	deletion
-	Gly 624	deletion
-	Asn 625	deletion
-	Ser 626	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	185308.3
Non-Polymers*	Number of molecules	4
	Total formula weight	2697.8
All*	Total formula weight	188006.2

*Water molecules are not included.