8U43

TRPV1 in nanodisc bound with PIP2-Br4

Summary for 8U43

Entry DOI	10.2210/pdb8u43/pdb
EMDB information	41873
Descriptor	Transient receptor potential cation channel subfamily V member 1, (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (5 entities in total)
Functional Keywords	trpv1 in nanodisc bound with pip2-br4 membrane protein, membrane protein
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	4
Total formula weight	300095.11
Authors	Arnold, W.R.,Julius, D.,Cheng, Y. (deposition date: 2023-09-08, release date: 2024-05-08, Last modification date: 2024-05-15)
Primary citation	Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y. Structural basis of TRPV1 modulation by endogenous bioactive lipids. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38698206 DOI: 10.1038/s41594-024-01299-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.4 Å)

Structure validation