3C5W

Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme

Summary for 3C5W

• Entry DOI: 10.2210/pdb3c5w/pdb
• Related: 3C5V
• Descriptor: PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1, ... (4 entities in total)
• Functional Keywords: methylesterase, phosphatase, pp2a, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : P30153 P67775
• Total number of polymer chains: 3
• Total formula weight: 95676.68

Authors

Xing, Y.,Li, Z.,Chen, Y.,Stock, J.,Jeffrey, P.D.,Shi, Y. (deposition date: 2008-02-01, release date: 2008-04-15, Last modification date: 2024-04-03)

• Primary citation: Xing, Y.,Li, Z.,Chen, Y.,Stock, J.B.,Jeffrey, P.D.,Shi, Y.; Structural mechanism of demethylation and inactivation of protein phosphatase 2A.; Cell(Cambridge,Mass.), 133:154-163, 2008; PubMed: 18394995; DOI: 10.1016/j.cell.2008.02.041

Experimental method

X-RAY DIFFRACTION (2.8 Å)