3C5W

Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PP2A A subunit	polymer	232	25896.3	1	UniProt (P30153) Pfam (PF02985)	Homo sapiens (human)
2	B (C)	PP2A C subunit	polymer	310	35693.2	1	UniProt (P67775) Pfam (PF00149)	Homo sapiens (human)
3	C (P)	PP2A-specific methylesterase PME-1	polymer	310	34087.2	1	UniProt (Q9Y570) Pfam (PF12697)	Homo sapiens (human)
4	D, E, F (A, C, P)	water	water		18.0	62	Chemie (HOH)

Sequence modifications

A: 9 - 46 (UniProt: P30153)

PDB	External Database	Details
Gly 5	-	expression tag
Ser 6	-	expression tag
His 7	-	expression tag
Met 8	-	expression tag

A: 400 - 589 (UniProt: P30153)
C: 1 - 309 (UniProt: P67775)

PDB	External Database	Details
Gly 0	-	expression tag

P: 39 - 238 (UniProt: Q9Y570)

PDB	External Database	Details
Gly 35	-	expression tag
Ser 36	-	expression tag
His 37	-	expression tag
Met 38	-	expression tag
Ala 156	Ser 156	SEE REMARK 999

P: 284 - 386 (UniProt: Q9Y570)

PDB	External Database	Details
Glu 239	-	SEE REMARK 999
Gly 240	-	SEE REMARK 999
Lys 283	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	95676.7
All*	Total formula weight	95676.7

*Water molecules are not included.