2HIU
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![BU of 2hiu by Molmil](/molmil-images/mine/2hiu) | NMR STRUCTURE OF HUMAN INSULIN IN 20% ACETIC ACID, ZINC-FREE, 10 STRUCTURES | Descriptor: | INSULIN | Authors: | Hua, Q.X, Gozani, S.N, Chance, R.E, Hoffmann, J.A, Frank, B.H, Weiss, M.A. | Deposit date: | 1996-10-08 | Release date: | 1997-04-01 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Structure of a protein in a kinetic trap. Nat.Struct.Biol., 2, 1995
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2JMN
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![BU of 2jmn by Molmil](/molmil-images/mine/2jmn) | NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 2006-11-21 | Release date: | 2006-12-05 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue. J.Mol.Biol., 264, 1996
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1VKT
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![BU of 1vkt by Molmil](/molmil-images/mine/1vkt) | HUMAN INSULIN TWO DISULFIDE MODEL, NMR, 10 STRUCTURES | Descriptor: | INSULIN | Authors: | Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 1996-10-14 | Release date: | 1997-04-01 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue. J.Mol.Biol., 264, 1996
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1XGL
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![BU of 1xgl by Molmil](/molmil-images/mine/1xgl) | HUMAN INSULIN DISULFIDE ISOMER, NMR, 10 STRUCTURES | Descriptor: | INSULIN | Authors: | Hua, Q.X, Gozani, S.N, Chance, R.E, Hoffmann, J.A, Frank, B.H, Weiss, M.A. | Deposit date: | 1996-10-10 | Release date: | 1997-04-01 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Structure of a protein in a kinetic trap. Nat.Struct.Biol., 2, 1995
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1LPH
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![BU of 1lph by Molmil](/molmil-images/mine/1lph) | LYS(B28)PRO(B29)-HUMAN INSULIN | Descriptor: | CHLORIDE ION, INSULIN, PHENOL, ... | Authors: | Ciszak, E, Beals, J.M, Frank, B.H, Baker, J.C, Carter, N.D, Smith, G.D. | Deposit date: | 1995-04-19 | Release date: | 1996-06-20 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Role of C-terminal B-chain residues in insulin assembly: the structure of hexameric LysB28ProB29-human insulin. Structure, 3, 1995
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1ZEI
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![BU of 1zei by Molmil](/molmil-images/mine/1zei) | CROSS-LINKED B28 ASP INSULIN | Descriptor: | CHLORIDE ION, INSULIN, M-CRESOL, ... | Authors: | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | Deposit date: | 1998-07-14 | Release date: | 1999-02-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues. Biochemistry, 37, 1998
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1BEN
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![BU of 1ben by Molmil](/molmil-images/mine/1ben) | INSULIN COMPLEXED WITH 4-HYDROXYBENZAMIDE | Descriptor: | 4-HYDROXYBENZAMIDE, CHLORIDE ION, HUMAN INSULIN, ... | Authors: | Smith, G.D, Ciszak, E, Pangborn, W. | Deposit date: | 1996-02-15 | Release date: | 1996-07-11 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | A novel complex of a phenolic derivative with insulin: structural features related to the T-->R transition. Protein Sci., 5, 1996
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1ZEG
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![BU of 1zeg by Molmil](/molmil-images/mine/1zeg) | STRUCTURE OF B28 ASP INSULIN IN COMPLEX WITH PHENOL | Descriptor: | CHLORIDE ION, INSULIN, PHENOL, ... | Authors: | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | Deposit date: | 1998-05-01 | Release date: | 1998-07-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues. Biochemistry, 37, 1998
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1ZEH
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![BU of 1zeh by Molmil](/molmil-images/mine/1zeh) | STRUCTURE OF INSULIN | Descriptor: | CHLORIDE ION, INSULIN, M-CRESOL, ... | Authors: | Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G. | Deposit date: | 1998-05-01 | Release date: | 1998-12-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues. Biochemistry, 37, 1998
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1J73
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![BU of 1j73 by Molmil](/molmil-images/mine/1j73) | Crystal structure of an unstable insulin analog with native activity. | Descriptor: | ZINC ION, insulin a, insulin b | Authors: | Wan, Z, Zhao, M, Nakagawa, S, Jia, W, Weiss, M.A. | Deposit date: | 2001-05-15 | Release date: | 2001-05-30 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. J.Mol.Biol., 315, 2002
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1JCA
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![BU of 1jca by Molmil](/molmil-images/mine/1jca) | Non-standard Design of Unstable Insulin Analogues with Enhanced Activity | Descriptor: | ZINC ION, insulin a, insulin b | Authors: | Weiss, M.A, Wan, Z, Zhao, M, Chu, Y.-C, Nakagawa, S.H, Burke, G.T, Jia, W, Hellmich, R, Katsoyannis, P.G. | Deposit date: | 2001-06-08 | Release date: | 2001-06-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. J.Mol.Biol., 315, 2002
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1KMF
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![BU of 1kmf by Molmil](/molmil-images/mine/1kmf) | NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES | Descriptor: | Insulin | Authors: | Xu, B, Hua, Q.X, Nakagawa, S.H, Jia, W, Chu, Y.C, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 2001-12-14 | Release date: | 2002-01-09 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue. J.Mol.Biol., 316, 2002
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1RWE
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![BU of 1rwe by Molmil](/molmil-images/mine/1rwe) | Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues | Descriptor: | CHLORIDE ION, Insulin, PHENOL, ... | Authors: | Wan, Z, Xu, B, Chu, Y.C, Li, B, Nakagawa, S.H, Qu, Y, Hu, S.Q, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 2003-12-16 | Release date: | 2005-02-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues. Biochemistry, 43, 2004
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