1HG7
 
 | | High resolution structure of HPLC-12 type III antifreeze protein from Ocean Pout Macrozoarces americanus | | Descriptor: | HPLC-12 TYPE III ANTIFREEZE PROTEIN, SULFATE ION | | Authors: | Antson, A.A, Smith, D.J, Roper, D.I, Lewis, S, Caves, L.S.D, Verma, C.S, Buckley, S.L, Lillford, P.J, Hubbard, R.E. | | Deposit date: | 2000-12-13 | | Release date: | 2001-01-31 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Understanding the Mechanism of Ice Binding by Type III Antifreeze Protein
J.Mol.Biol., 305, 2001
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1BYG
 | | KINASE DOMAIN OF HUMAN C-TERMINAL SRC KINASE (CSK) IN COMPLEX WITH INHIBITOR STAUROSPORINE | | Descriptor: | PROTEIN (C-TERMINAL SRC KINASE), STAUROSPORINE | | Authors: | Antson, A.A, Lamers, M.B.A.C, Scott, R.K, Williams, D.H, Hubbard, R.E. | | Deposit date: | 1998-10-14 | | Release date: | 1999-10-14 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the protein tyrosine kinase domain of C-terminal Src kinase (CSK) in complex with staurosporine.
J.Mol.Biol., 285, 1999
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1C9S
 | | CRYSTAL STRUCTURE OF A COMPLEX OF TRP RNA-BINDING ATTENUATION PROTEIN WITH A 53-BASE SINGLE STRANDED RNA CONTAINING ELEVEN GAG TRIPLETS SEPARATED BY AU DINUCLEOTIDES | | Descriptor: | SINGLE STRANDED RNA (55-MER), TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN | | Authors: | Antson, A.A, Dodson, E.J, Dodson, G.G, Greaves, R.B, Chen, X.-P, Gollnick, P. | | Deposit date: | 1999-08-03 | | Release date: | 1999-09-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA.
Nature, 401, 1999
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4ZC3
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1WAP
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1DTO
 | | CRYSTAL STRUCTURE OF THE COMPLETE TRANSACTIVATION DOMAIN OF E2 PROTEIN FROM THE HUMAN PAPILLOMAVIRUS TYPE 16 | | Descriptor: | REGULATORY PROTEIN E2 | | Authors: | Antson, A.A, Burns, J.E, Moroz, O.V, Scott, D.J, Sanders, C.M, Bronstein, I.B, Dodson, G.G, Wilson, K.S, Maitland, N. | | Deposit date: | 2000-01-13 | | Release date: | 2000-02-23 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the intact transactivation domain of the human papillomavirus E2 protein.
Nature, 403, 2000
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2TPL
 | | TYROSINE PHENOL-LYASE FROM CITROBACTER INTERMEDIUS COMPLEX WITH 3-(4'-HYDROXYPHENYL)PROPIONIC ACID, PYRIDOXAL-5'-PHOSPHATE AND CS+ ION | | Descriptor: | CESIUM ION, HYDROXYPHENYL PROPIONIC ACID, TYROSINE PHENOL-LYASE | | Authors: | Antson, A.A, Demidkina, T.V, Wilson, K.S. | | Deposit date: | 1997-01-23 | | Release date: | 1997-04-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity.
Biochemistry, 36, 1997
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1GZI
 | | CRYSTAL STRUCTURE OF TYPE III ANTIFREEZE PROTEIN FROM OCEAN POUT, AT 1.8 ANGSTROM RESOLUTION | | Descriptor: | HPLC-12 TYPE III ANTIFREEZE PROTEIN | | Authors: | Antson, A.A, Lewis, S, Roper, D.I, Smith, D.J, Hubbard, R.E. | | Deposit date: | 1996-10-25 | | Release date: | 1997-09-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Structure of Type III Antifreeze Protein from Ocean Pout
To be Published
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8POP
 | | HK97 small terminase in complex with DNA | | Descriptor: | DNA (31-MER), Terminase small subunit | | Authors: | Chechik, M, Greive, S.J, Antson, A.A, Jenkins, H.T. | | Deposit date: | 2023-07-05 | | Release date: | 2023-08-09 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis for DNA recognition by a viral genome-packaging machine.
Proc.Natl.Acad.Sci.USA, 121, 2024
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4V4F
 | | The structure of the trp RNA-binding attenuation protein (TRAP) bound to a RNA molecule containing UAGAU repeats | | Descriptor: | 5'-R(*UP*AP*GP*AP*UP)-3', TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN | | Authors: | Hopcroft, N.H, Manfredo, A, Wendt, A.L, Brzozowski, A.M, Gollnick, P, Antson, A.A. | | Deposit date: | 2003-12-08 | | Release date: | 2014-07-09 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Interaction of RNA with Trap: The Role of Triplet Repeats and Separating Spacer Nucleotides
J.Mol.Biol., 338, 2004
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8CKB
 | | Asymmetric reconstruction of the crAss001 virion | | Descriptor: | Auxiliary capsid protein gp36, Cargo protein 1 gp45, Head fiber dimer protein gp29, ... | | Authors: | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | | Deposit date: | 2023-02-16 | | Release date: | 2023-11-22 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.39 Å) | | Cite: | Structural atlas of the most abundant human gut virus
Nature
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7NT6
 | | CryoEM structure of the Nipah virus nucleocapsid spiral clam-shaped assembly | | Descriptor: | Nucleoprotein, RNA (42-MER), RNA (48-MER) | | Authors: | Ker, D.S, Jenkins, H.T, Greive, S.J, Antson, A.A. | | Deposit date: | 2021-03-09 | | Release date: | 2021-07-07 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | CryoEM structure of the Nipah virus nucleocapsid assembly.
Plos Pathog., 17, 2021
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8CFA
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8CEZ
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5M1N
 | | Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Manganese | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, Phage terminase large subunit, ... | | Authors: | Xu, R.G, Jenkins, H.T, Chechik, M, Blagova, E.V, Greive, S.J, Antson, A.A. | | Deposit date: | 2016-10-09 | | Release date: | 2016-10-26 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism.
Nucleic Acids Res., 45, 2017
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2WV1
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7NT5
 | | CryoEM structure of the Nipah virus nucleocapsid single helical turn assembly | | Descriptor: | Nucleoprotein, RNA (78-MER) | | Authors: | Ker, D.S, Jenkins, H.T, Greive, S.J, Antson, A.A. | | Deposit date: | 2021-03-09 | | Release date: | 2021-07-07 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | CryoEM structure of the Nipah virus nucleocapsid assembly.
Plos Pathog., 17, 2021
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9FFH
 | | Native capsid of Rhodobacter microvirus Ebor computed with I4 symmetry | | Descriptor: | Major capsid protein | | Authors: | Bardy, P, MacDonald, C.I.W, Jenkins, H.T, Chechik, M, Hart, S.J, Turkenburg, J.P, Blaza, J.N, Fogg, P.C.M, Antson, A.A. | | Deposit date: | 2024-05-23 | | Release date: | 2024-06-12 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | A stargate mechanism of Microviridae genome delivery unveiled by cryogenic electron tomography.
Biorxiv, 2024
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9FFG
 | | Empty capsid of Rhodobacter microvirus Ebor computed with I4 symmetry | | Descriptor: | Major capsid protein | | Authors: | Bardy, P, MacDonald, C.I.W, Jenkins, H.T, Byrom, L, Chechik, M, Hart, S.J, Turkenburg, J.P, Blaza, J.N, Fogg, P.C.M, Antson, A.A. | | Deposit date: | 2024-05-23 | | Release date: | 2024-06-12 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | A stargate mechanism of Microviridae genome delivery unveiled by cryogenic electron tomography.
Biorxiv, 2024
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1AX4
 | | TRYPTOPHANASE FROM PROTEUS VULGARIS | | Descriptor: | POTASSIUM ION, TRYPTOPHANASE | | Authors: | Isupov, M.N, Antson, A.A, Dodson, E.J, Dodson, G.G, Dementieva, I.S, Zakomirdina, L.N, Wilson, K.S, Dauter, Z, Lebedev, A.A, Harutyunyan, E.H. | | Deposit date: | 1997-10-28 | | Release date: | 1998-01-28 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of tryptophanase.
J.Mol.Biol., 276, 1998
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4XP7
 | | Crystal structure of Human tRNA dihydrouridine synthase 2 | | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | | Authors: | Whelan, F, Jenkins, H.T, Griffiths, S, Byrne, R.T, Dodson, E.J, Antson, A.A. | | Deposit date: | 2015-01-16 | | Release date: | 2015-01-28 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | From bacterial to human dihydrouridine synthase: automated structure determination.
Acta Crystallogr.,Sect.D, 71, 2015
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4XVN
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6Z6E
 | | Crystal structure of the HK97 bacteriophage small terminase | | Descriptor: | IODIDE ION, Terminase small subunit | | Authors: | Fung, H.K.H, Chechik, M, Baumann, C.G, Antson, A.A. | | Deposit date: | 2020-05-28 | | Release date: | 2021-06-09 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system.
Nucleic Acids Res., 50, 2022
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6Z6D
 | | Crystal structure of the HK97 bacteriophage large terminase | | Descriptor: | BROMIDE ION, Terminase large subunit | | Authors: | Fung, H.K.H, Chechik, M, Baumann, C.G, Antson, A.A. | | Deposit date: | 2020-05-28 | | Release date: | 2021-06-09 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system.
Nucleic Acids Res., 50, 2022
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1GQM
 | | The structure of S100A12 in a hexameric form and its proposed role in receptor signalling | | Descriptor: | CALCIUM ION, CALGRANULIN C | | Authors: | Moroz, O.V, Antson, A.A, Dodson, E.G, Burrel, H.J, Grist, S.J, Lloyd, R.M, Maitland, N.J, Dodson, G.G, Wilson, K.S, Lukanidin, E, Bronstein, I.B. | | Deposit date: | 2001-11-26 | | Release date: | 2002-02-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Structure of S100A12 in a Hexameric Form and its Proposed Role in Receptor Signalling
Acta Crystallogr.,Sect.D, 58, 2002
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