1ZEG

STRUCTURE OF B28 ASP INSULIN IN COMPLEX WITH PHENOL

Summary for 1ZEG

DescriptorINSULIN, PHENOL, ZINC ION, ... (6 entities in total)
Functional Keywordshormone, metabolic role, chemical activity, insulin mutant, cross-link, glucose metabolism, diabetes
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight12155.31
Authors
Whittingham, J.L.,Edwards, E.J.,Antson, A.A.,Clarkson, J.M.,Dodson, G.G. (deposition date: 1998-05-01, release date: 1998-07-15, Last modification date: 2011-07-13)
Primary citation
Whittingham, J.L.,Edwards, D.J.,Antson, A.A.,Clarkson, J.M.,Dodson, G.G.
Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37:11516-11523, 1998
PubMed: 9708987 (PDB entries with the same primary citation)
DOI: 10.1021/bi980807s
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.6 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers61.1%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report