6CM3
 
 | | BG505 SOSIP in complex with sCD4, 17b, 8ANC195 | | Descriptor: | 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, H, Bjorkman, P.J. | | Deposit date: | 2018-03-02 | | Release date: | 2018-10-17 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion.
Cell Host Microbe, 24, 2018
|
|
6CHB
 | |
7RKS
 | | Structure of the SARS-CoV receptor binding domain in complex with the human neutralizing antibody Fab fragment, C118 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, C118 Antibody Fab Heavy Chain, ... | | Authors: | Jette, C.A, Bjorkman, P.J, Barnes, C.O. | | Deposit date: | 2021-07-22 | | Release date: | 2021-09-22 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Cell Rep, 36, 2021
|
|
7RKV
 | | Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C118 Fab Heavy Chain, C118 Fab Light Chain, ... | | Authors: | Barnes, C.O, Jette, C.A, Bjorkman, P.J. | | Deposit date: | 2021-07-22 | | Release date: | 2021-09-22 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Cell Rep, 36, 2021
|
|
7RKU
 | | Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C022 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C022 Antibody Fab Heavy Chain, C022 Antibody Fab Light Chain, ... | | Authors: | Jette, C.A, Bjorkman, P.J, Barnes, C.O. | | Deposit date: | 2021-07-22 | | Release date: | 2021-09-22 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Cell Rep, 36, 2021
|
|
7RFB
 | | Crystal structure of broadly neutralizing antibody mAb1198 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Flyak, A.I, Bjorkman, P.J. | | Deposit date: | 2021-07-14 | | Release date: | 2022-01-12 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization.
Immunity, 55, 2022
|
|
7RFC
 | |
2GJ7
 | | Crystal Structure of a gE-gI/Fc complex | | Descriptor: | Glycoprotein E, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J. | | Deposit date: | 2006-03-30 | | Release date: | 2006-05-30 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (5 Å) | | Cite: | Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging.
Plos Biol., 4, 2006
|
|
2GIY
 | |
2GSG
 | | Crystal structure of the Fv fragment of a monoclonal antibody specific for poly-glutamine | | Descriptor: | SULFATE ION, monoclonal antibody heavy chain, monoclonal antibody light chain | | Authors: | Li, P, Huey-Tubman, K.E, West Jr, A.P, Bennett, M.J, Bjorkman, P.J. | | Deposit date: | 2006-04-26 | | Release date: | 2007-04-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The structure of a polyQ-anti-polyQ complex reveals binding according to a linear lattice model.
Nat.Struct.Mol.Biol., 14, 2007
|
|
2GW5
 | | Crystal Structure of LIR-2 (ILT4) at 1.8 : differences from LIR-1 (ILT2) in regions implicated in the binding of the Cytomegalovirus class I MHC homolog UL18 | | Descriptor: | ISOPROPYL ALCOHOL, Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor | | Authors: | Willcox, B.E, Thomas, L.M, Chapman, T.L, Heikema, A.P, West, A.P, Bjorkman, P.J. | | Deposit date: | 2006-05-03 | | Release date: | 2006-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of LIR-2 (ILT4) at 1.8 A: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18.
Bmc Struct.Biol., 2, 2002
|
|
6MEE
 | | Crystal structure of broadly neutralizing antibody HEPC74 | | Descriptor: | antibody HEPC74 Heavy Chain, antibody HEPC74 Light Chain | | Authors: | Flyak, A.I, Bjorkman, P.J. | | Deposit date: | 2018-09-06 | | Release date: | 2018-11-21 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
|
|
6MEJ
 | |
6MEK
 | |
6MEF
 | | Crystal structure of broadly neutralizing antibody AR3C | | Descriptor: | antibody AR3C Heavy Chain, antibody AR3C Light Chain | | Authors: | Flyak, A.I, Bjorkman, P.J. | | Deposit date: | 2018-09-06 | | Release date: | 2018-11-21 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
|
|
6MED
 | | Crystal structure of broadly neutralizing antibody HEPC3 | | Descriptor: | SULFATE ION, antibody HEPC3 Heavy Chain, antibody HEPC3 Light Chain | | Authors: | Flyak, A.I, Bjorkman, P.J. | | Deposit date: | 2018-09-06 | | Release date: | 2018-11-21 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
|
|
6MEI
 | |
1Z8L
 | | Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Davis, M.I, Bennett, M.J, Thomas, L.M, Bjorkman, P.J. | | Deposit date: | 2005-03-30 | | Release date: | 2005-04-19 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase
Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
1W9R
 | | Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae | | Descriptor: | CHOLINE BINDING PROTEIN A | | Authors: | Luo, R, Mann, B, Lewis, W.S, Rowe, A, Heath, R, Stewart, M.L, Hamburger, A.E, Bjorkman, P.J, Sivakolundu, S, Lacy, E.R, Tuomanen, E, Kriwacki, R.W. | | Deposit date: | 2004-10-15 | | Release date: | 2005-02-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Choline Binding Protein A, the Major Adhesin of Streptococcus Pneumoniae
Embo J., 24, 2005
|
|
1Z6O
 | | Crystal Structure of Trichoplusia ni secreted ferritin | | Descriptor: | CALCIUM ION, FE (III) ION, Ferritin heavy chain, ... | | Authors: | Hamburger, A.E, West Jr, A.P, Hamburger, Z.A, Hamburger, P, Bjorkman, P.J. | | Deposit date: | 2005-03-22 | | Release date: | 2005-05-24 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains.
J.Mol.Biol., 349, 2005
|
|
6MEG
 | | Crystal structure of human monoclonal antibody HEPC46 | | Descriptor: | antibody HEPC46 Heavy Chain, antibody HEPC46 Light Chain | | Authors: | Flyak, A.I, Bjorkman, P.J. | | Deposit date: | 2018-09-06 | | Release date: | 2018-11-21 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
|
|
6MEH
 | |
1XED
 | |
1ZS8
 | | Crystal Structure of the Murine MHC Class Ib Molecule M10.5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, histocompatibility 2, ... | | Authors: | Olson, R, Huey-Tubman, K.E, Dulac, C, Bjorkman, P.J. | | Deposit date: | 2005-07-22 | | Release date: | 2005-07-26 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of a pheromone receptor-associated MHC molecule with an open and empty groove.
Plos Biol., 3, 2005
|
|
4GW4
 | | Crystal structure of 3BNC60 Fab with P61A mutation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC60 Fab Heavy-chain, 3BNC60 Fab Light-chain | | Authors: | Diskin, R, Fu, B.Z, Bjorkman, P.J. | | Deposit date: | 2012-08-31 | | Release date: | 2013-04-17 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization.
Cell(Cambridge,Mass.), 153, 2013
|
|
