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2GSG

Crystal structure of the Fv fragment of a monoclonal antibody specific for poly-glutamine

Summary for 2GSG
Entry DOI10.2210/pdb2gsg/pdb
Descriptormonoclonal antibody light chain, monoclonal antibody heavy chain, SULFATE ION, ... (4 entities in total)
Functional Keywordsfv, monoclonal antibody, poly-glutamine, immune system
Biological sourceMus musculus (house mouse)
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Total number of polymer chains4
Total formula weight51949.85
Authors
Li, P.,Huey-Tubman, K.E.,West Jr., A.P.,Bennett, M.J.,Bjorkman, P.J. (deposition date: 2006-04-26, release date: 2007-04-24, Last modification date: 2011-07-13)
Primary citationLi, P.,Huey-Tubman, K.E.,Gao, T.,Li, X.,West Jr., A.P.,Bennett, M.J.,Bjorkman, P.J.
The structure of a polyQ-anti-polyQ complex reveals binding according to a linear lattice model.
Nat.Struct.Mol.Biol., 14:381-387, 2007
Cited by
PubMed: 17450152
DOI: 10.1038/nsmb1234
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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