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6MED

Crystal structure of broadly neutralizing antibody HEPC3

Summary for 6MED
Entry DOI10.2210/pdb6med/pdb
Descriptorantibody HEPC3 Heavy Chain, antibody HEPC3 Light Chain, SULFATE ION, ... (4 entities in total)
Functional Keywordshcv glycoprotein, broadly neutralizing antibodies, immune system
Biological sourceHomo sapiens
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Total number of polymer chains6
Total formula weight146986.26
Authors
Flyak, A.I.,Bjorkman, P.J. (deposition date: 2018-09-06, release date: 2018-11-21, Last modification date: 2023-10-11)
Primary citationFlyak, A.I.,Ruiz, S.,Colbert, M.D.,Luong, T.,Crowe Jr., J.E.,Bailey, J.R.,Bjorkman, P.J.
HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24:703-716.e3, 2018
Cited by
PubMed: 30439340
DOI: 10.1016/j.chom.2018.10.009
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.04 Å)
Structure validation

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