7RKS

Structure of the SARS-CoV receptor binding domain in complex with the human neutralizing antibody Fab fragment, C118

Summary for 7RKS

• Entry DOI: 10.2210/pdb7rks/pdb
• Descriptor: C118 Antibody Fab Heavy Chain, C118 Antibody Fab Light Chain, Spike protein S1, ... (5 entities in total)
• Functional Keywords: antibody, surface protein, fab, coronavirus, fusion protein, binding domain, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 142586.78

Authors

Jette, C.A.,Bjorkman, P.J.,Barnes, C.O. (deposition date: 2021-07-22, release date: 2021-09-22, Last modification date: 2023-10-18)

• Primary citation: Jette, C.A.,Cohen, A.A.,Gnanapragasam, P.N.P.,Muecksch, F.,Lee, Y.E.,Huey-Tubman, K.E.,Schmidt, F.,Hatziioannou, T.,Bieniasz, P.D.,Nussenzweig, M.C.,West Jr., A.P.,Keeffe, J.R.,Bjorkman, P.J.,Barnes, C.O.; Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.; Cell Rep, 36:109760-109760, 2021; PubMed: 34534459; DOI: 10.1016/j.celrep.2021.109760

Experimental method

X-RAY DIFFRACTION (2.7 Å)