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7LCC
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BU of 7lcc by Molmil
Helitron transposase bound to LTS
Descriptor: Helraiser K1068Q, LTS, ZINC ION
Authors:Kosek, D, Dyda, F.
Deposit date:2021-01-10
Release date:2021-08-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:The large bat Helitron DNA transposase forms a compact monomeric assembly that buries and protects its covalently bound 5'-transposon end.
Mol.Cell, 81, 2021
7NHU
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BU of 7nhu by Molmil
Crystal structure of desB30 insulin produced by cell free protein synthesis
Descriptor: Insulin
Authors:Johansson, E.
Deposit date:2021-02-11
Release date:2021-06-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Cell free protein synthesis versus yeast expression - A comparison using insulin as a model protein.
Protein Expr.Purif., 186, 2021
7NMU
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BU of 7nmu by Molmil
Crystal structure of human platelet glycoprotein VI in complex with an inhibitory nanobody.
Descriptor: CALCIUM ION, Nanobody 2, Platelet glycoprotein VI
Authors:Slater, A, Jonas, E, Watson, S.P.
Deposit date:2021-02-23
Release date:2021-03-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer.
Blood, 137, 2021
6WH4
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BU of 6wh4 by Molmil
Crystal structure of HTR2A with inverse agonist
Descriptor: 1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine, 5-hydroxytryptamine receptor 2A,Soluble cytochrome b562 fusion, CHOLESTEROL, ...
Authors:Kim, K.L, Che, T, Krumm, B.E, Roth, B.L.
Deposit date:2020-04-07
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of a Hallucinogen-Activated Gq-Coupled 5-HT 2A Serotonin Receptor
Cell(Cambridge,Mass.), 182, 2020
6WGT
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BU of 6wgt by Molmil
Crystal structure of HTR2A with hallucinogenic agonist
Descriptor: (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 2A,Soluble cytochrome b562 fusion, CHOLESTEROL, ...
Authors:Kim, K.L, Che, T, Krumm, B.E, Roth, B.L.
Deposit date:2020-04-06
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of a Hallucinogen-Activated Gq-Coupled 5-HT 2A Serotonin Receptor
Cell(Cambridge,Mass.), 182, 2020
7KKZ
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BU of 7kkz by Molmil
Crystal structure of mouse anti-HIV potent neutralizing antibody M4H2K1
Descriptor: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Heavy chain of Fab fragment of mouse monoclonal antibody M4H2K1, ...
Authors:Kumar, S, Wilson, I.A.
Deposit date:2020-10-28
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
7KMD
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BU of 7kmd by Molmil
Crystal structure of a HIV-1 clade C isolate Du172.17 HR1.R4.664 Env trimer in complex with human Fabs PGT124 and 35O22
Descriptor: 124 Heavy chain, 124 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kumar, S, Wilson, I.A.
Deposit date:2020-11-02
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.39228582 Å)
Cite:Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
7KLC
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BU of 7klc by Molmil
Crystal structure of M4H2K1 Fab bound to HIV-1 BG505 gp120 core and to 17b Fab
Descriptor: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kumar, S, Wilson, I.A.
Deposit date:2020-10-29
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
7LOK
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BU of 7lok by Molmil
Structure of CD4 mimetic M48U1 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab
Descriptor: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jette, C.A, Bjorkman, P.J.
Deposit date:2021-02-10
Release date:2021-04-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
Nat Commun, 12, 2021
7LO6
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BU of 7lo6 by Molmil
Structure of CD4 mimetic BNM-III-170 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab
Descriptor: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jette, C.A, Bjorkman, P.J.
Deposit date:2021-02-09
Release date:2021-04-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
Nat Commun, 12, 2021
7LHE
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BU of 7lhe by Molmil
Structure of full-length IP3R1 channel reconstituted into lipid nanodisc in the apo-state
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION
Authors:Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I.
Deposit date:2021-01-22
Release date:2021-06-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of type 1 IP3R channel in a lipid bilayer
Commun Biol, 4, 2021
7LHF
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BU of 7lhf by Molmil
Structure of full-length IP3R1 channel solubilized in LNMG & lipid in the apo-state
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION
Authors:Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I.
Deposit date:2021-01-22
Release date:2021-06-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Cryo-EM structure of type 1 IP3R channel in a lipid bilayer
Commun Biol, 4, 2021
7LRT
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BU of 7lrt by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 spike glycoprotein, ...
Authors:Zhou, T, Tsybovsky, T.
Deposit date:2021-02-17
Release date:2021-07-14
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Science, 373, 2021
7LRS
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BU of 7lrs by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain
Descriptor: Spike glycoprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, antibody A23-58.1 heavy chain, ...
Authors:Zhou, T, Tsybovsky, Y.
Deposit date:2021-02-17
Release date:2021-07-14
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Science, 373, 2021
7KPJ
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BU of 7kpj by Molmil
Crystal structure of Ruminococcus gnavus immunoglobulin binding protein in complex with 338E6 Fab
Descriptor: 338E6 Fab heavy chain, 338E6 Fab light chain kappa, CALCIUM ION, ...
Authors:Borowska, M.T, Adams, E.J.
Deposit date:2020-11-11
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The molecular characterization of antibody binding to a superantigen-like protein from a commensal microbe.
Proc.Natl.Acad.Sci.USA, 118, 2021
2W1W
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BU of 2w1w by Molmil
Native structure of a family 35 carbohydrate binding module from Clostridium thermocellum
Descriptor: CALCIUM ION, GLYCEROL, LIPOLYTIC ENZYME, ...
Authors:Gloster, T.M, Davies, G.J, Correia, M, Prates, J, Fontes, C, Gilbert, H.J.
Deposit date:2008-10-21
Release date:2009-01-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2W3J
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BU of 2w3j by Molmil
Structure of a family 35 carbohydrate binding module from an environmental isolate
Descriptor: CALCIUM ION, CARBOHYDRATE BINDING MODULE
Authors:Montainer, C, Flint, J, Gloster, T.M, Turkenburg, J.P, Davies, G.J, Gilbert, H.J.
Deposit date:2008-11-12
Release date:2009-01-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2X6G
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BU of 2x6g by Molmil
X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A)
Descriptor: C-C MOTIF CHEMOKINE 3
Authors:Guo, Q, Ren, M, Tang, W.
Deposit date:2010-02-17
Release date:2010-11-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Polymerization of Mip-1 Chemokine (Ccl3 and Ccl4) and Clearance of Mip-1 by Insulin-Degrading Enzyme.
Embo J., 29, 2010
2X6L
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BU of 2x6l by Molmil
X-ray Structure of Macrophage Inflammatory Protein-1 beta
Descriptor: C-C MOTIF CHEMOKINE 4, GLYCEROL
Authors:Guo, Q, Ren, M, Tang, W.
Deposit date:2010-02-17
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:Polymerization of Mip-1 Chemokine (Ccl3 and Ccl4) and Clearance of Mip-1 by Insulin-Degrading Enzyme.
Embo J., 29, 2010
2X69
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BU of 2x69 by Molmil
X-ray Structure of Macrophage Inflammatory Protein-1 alpha polymer
Descriptor: C-C MOTIF CHEMOKINE 3
Authors:Guo, Q, Ren, M, Tang, W.
Deposit date:2010-02-15
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Polymerization of Mip-1 Chemokine (Ccl3 and Ccl4) and Clearance of Mip-1 by Insulin-Degrading Enzyme.
Embo J., 29, 2010
2WKO
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BU of 2wko by Molmil
Structure of metal loaded Pathogenic SOD1 Mutant G93A.
Descriptor: COPPER (II) ION, IODIDE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
Authors:Antonyuk, S.V, Galaleldeen, A, Strange, R, Whitson, L, Narayana, N, Taylor, A, Schuermann, J.P, Holloway, S.P, Hasnain, S.S, Hart, P.J.
Deposit date:2009-06-16
Release date:2009-11-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural and Biophysical Properties of Metal-Free Pathogenic Sod1 Mutants A4V and G93A.
Arch.Biochem.Biophys., 492, 2009
2WK3
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BU of 2wk3 by Molmil
Crystal structure of human insulin-degrading enzyme in complex with amyloid-beta (1-42)
Descriptor: BETA-AMYLOID PROTEIN 42, INSULIN DEGRADING ENZYME, ZINC ION
Authors:Guo, Q, Tang, W.J.
Deposit date:2009-06-05
Release date:2009-11-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Molecular Basis for the Recognition and Cleavages of Igf-II, Tgf-Alpha, and Amylin by Human Insulin Degrading Enzyme.
J.Mol.Biol., 395, 2010
2XNU
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BU of 2xnu by Molmil
Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors
Descriptor: 2-(2-(4-PHENYLPIPERIDIN-1-YL)ETHYL)-1H-INDOLE, SOLUBLE ACETYLCHOLINE RECEPTOR
Authors:Rucktooa, P, Akdemir, A, deEsch, I, Sixma, T.K.
Deposit date:2010-08-06
Release date:2011-08-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Acetylcholine Binding Protein (Achbp) as Template for Hierarchical in Silico Screening Procedures to Identify Structurally Novel Ligands for the Nicotinic Receptors.
Bioorg.Med.Chem., 19, 2011
2Y29
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BU of 2y29 by Molmil
Structure of segment KLVFFA from the amyloid-beta peptide (Ab, residues 16-21), alternate polymorph III
Descriptor: AMYLOID BETA A4 PROTEIN
Authors:Colletier, J, Laganowsky, A, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-12-14
Release date:2011-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Basis for Amyloid-{Beta} Polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
2Y58
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BU of 2y58 by Molmil
Fragment growing induces conformational changes in acetylcholine- binding protein: A structural and thermodynamic analysis - (Compound 6)
Descriptor: CHLORIDE ION, SOLUBLE ACETYLCHOLINE RECEPTOR, SULFATE ION, ...
Authors:Rucktooa, P, Edink, E, deEsch, I.J.P, Sixma, T.K.
Deposit date:2011-01-12
Release date:2011-06-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis.
J.Am.Chem.Soc., 133, 2011

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