6WGT

Crystal structure of HTR2A with hallucinogenic agonist

Summary for 6WGT

Entry DOI	10.2210/pdb6wgt/pdb
Descriptor	5-hydroxytryptamine receptor 2A,Soluble cytochrome b562 fusion, (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, CHOLESTEROL, ... (7 entities in total)
Functional Keywords	htr2a, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	154931.17
Authors	Kim, K.L.,Che, T.,Krumm, B.E.,Roth, B.L. (deposition date: 2020-04-06, release date: 2020-09-23, Last modification date: 2023-10-18)
Primary citation	Kim, K.L.,Che, T.,Panova, O.,DiBerto, J.F.,Lyu, J.,Krumm, B.E.,Wacker, D.,Robertson, M.J.,Seven, A.B.,Nichols, D.E.,Shoichet, B.K.,Skiniotis, G.,Roth, B.L. Structure of a Hallucinogen-Activated Gq-Coupled 5-HT 2A Serotonin Receptor Cell(Cambridge,Mass.), 182:1574-1588, 2020 Cited by DOI: 10.1016/j.cell.2020.08.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.4 Å)

Structure validation