2X69

X-ray Structure of Macrophage Inflammatory Protein-1 alpha polymer

Summary for 2X69

• Entry DOI: 10.2210/pdb2x69/pdb
• Related: 1B50 1B53 2X6G
• Descriptor: C-C MOTIF CHEMOKINE 3 (2 entities in total)
• Functional Keywords: immune system, inflammatory response, cytokine, chemotaxis
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted: P10147
• Total number of polymer chains: 5
• Total formula weight: 38968.32

Authors

Guo, Q.,Ren, M.,Tang, W. (deposition date: 2010-02-15, release date: 2010-11-03, Last modification date: 2011-07-13)

• Primary citation: Ren, M.,Guo, Q.,Guo, L.,Lenz, M.,Qian, F.,Koenen, R.R.,Xu, H.,Schilling, A.B.,Weber, C.,Ye, R.D.,Dinner, A.R.,Tang, W.; Polymerization of Mip-1 Chemokine (Ccl3 and Ccl4) and Clearance of Mip-1 by Insulin-Degrading Enzyme.; Embo J., 29:3952-, 2010; PubMed: 20959807; DOI: 10.1038/EMBOJ.2010.256

Experimental method

X-RAY DIFFRACTION (2.65 Å)