2WKO

Structure of metal loaded Pathogenic SOD1 Mutant G93A.

Summary for 2WKO

Related1L3N 2AF2 1UXL 1PTZ 1OEZ 2VR8 1RK7 2VR7 1HL4 1AZV 2C9S 1MFM 2V0A 4SOD 1OZU 1DSW 2VR6 1KMG 1OZT 2C9V 1N18 1BA9 1PU0 1FUN 1SOS 1N19 2C9U 1HL5 1P1V 1SPD 1UXM 3GZO 3GZP 3GZQ
DescriptorSUPEROXIDE DISMUTASE [CU-ZN], COPPER (II) ION, ZINC ION, ... (6 entities in total)
Functional Keywordsamyotrophic lateral sclerosis, phosphoprotein, oxidoreductase, disease mutation, neurodegeneration, acetylation, antioxidant, metal-binding
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm P00441 P00441
Total number of polymer chains2
Total molecular weight32389.87
Authors
Antonyuk, S.V.,Galaleldeen, A.,Strange, R.,Whitson, L.,Narayana, N.,Taylor, A.,Schuermann, J.P.,Holloway, S.P.,Hasnain, S.S.,Hart, P.J. (deposition date: 2009-06-16, release date: 2009-11-24, Last modification date: 2011-07-13)
Primary citation
Galaleldeen, A.,Strange, R.W.,Whitson, L.J.,Antonyuk, S.V.,Narayana, N.,Taylor, A.B.,Schuermann, J.P.,Holloway, S.P.,Hasnain, S.S.,Hart, P.J.
Structural and Biophysical Properties of Metal-Free Pathogenic Sod1 Mutants A4V and G93A.
Arch.Biochem.Biophys., 492:40-, 2009
PubMed: 19800308 (PDB entries with the same primary citation)
DOI: 10.1016/J.ABB.2009.09.020
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.97 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.237703.0%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report