1N18

Thermostable mutant of Human Superoxide Dismutase, C6A, C111S

Summary for 1N18

• Entry DOI: 10.2210/pdb1n18/pdb
• Related: 1M19
• Descriptor: Superoxide dismutase [Cu-Zn], COPPER (I) ION, ZINC ION, ... (5 entities in total)
• Functional Keywords: greek key beta barrel, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00441
• Total number of polymer chains: 10
• Total formula weight: 160491.89

Authors

Cardoso, R.M.F.,Thayer, M.M.,DiDonato, M.,Lo, T.P.,Bruns, C.K.,Getzoff, E.D.,Tainer, J.A. (deposition date: 2002-10-16, release date: 2002-11-27, Last modification date: 2021-10-27)

• Primary citation: Cardoso, R.M.F.,Thayer, M.M.,DiDonato, M.,Lo, T.P.,Bruns, C.K.,Getzoff, E.D.,Tainer, J.A.; Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase.; J.Mol.Biol., 324:247-256, 2002; PubMed: 12441104; DOI: 10.1016/S0022-2836(02)01090-2

Experimental method

X-RAY DIFFRACTION (2 Å)