7LOK
Structure of CD4 mimetic M48U1 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab
Summary for 7LOK
Entry DOI | 10.2210/pdb7lok/pdb |
Related | 7LO6 |
EMDB information | 23462 23465 |
Descriptor | Envelope glycoprotein BG505 SOSIP.664 gp120, Envelope Glycoprotein BG505 SOSIP.664 gp41, 17b Fab Light Chain, ... (9 entities in total) |
Functional Keywords | hiv-1, fusion, entry, membrane, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 13 |
Total formula weight | 325001.59 |
Authors | |
Primary citation | Jette, C.A.,Barnes, C.O.,Kirk, S.M.,Melillo, B.,Smith III, A.B.,Bjorkman, P.J. Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation. Nat Commun, 12:1950-1950, 2021 Cited by PubMed: 33782388DOI: 10.1038/s41467-021-21816-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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