7KLC

Crystal structure of M4H2K1 Fab bound to HIV-1 BG505 gp120 core and to 17b Fab

Summary for 7KLC

• Entry DOI: 10.2210/pdb7klc/pdb
• Related: 7KKZ
• Descriptor: M4H2K1 Fab heavy chain, M4H2K1 Fab light chain, 17b Fab light chain, ... (9 entities in total)
• Functional Keywords: mouse antibody, immune system, anti-hiv1 neutralizing antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 5
• Total formula weight: 142457.76

Authors

Kumar, S.,Wilson, I.A. (deposition date: 2020-10-29, release date: 2021-07-07, Last modification date: 2023-10-18)

• Primary citation: Kumar, S.,Lin, X.,Ngo, T.,Shapero, B.,Sou, C.,Allen, J.D.,Copps, J.,Zhang, L.,Ozorowski, G.,He, L.,Crispin, M.,Ward, A.B.,Wilson, I.A.,Zhu, J.; Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.; Mbio, 12:e0042921-e0042921, 2021; PubMed: 34156262; DOI: 10.1128/mBio.00429-21

Experimental method

X-RAY DIFFRACTION (4.3 Å)