1Z3I
 
 | | Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54 | | 分子名称: | SULFATE ION, ZINC ION, similar to RAD54-like | | 著者 | Thoma, N.H, Czyzewski, B.K, Alexeev, A.A, Mazin, A.V, Kowalczykowski, S.C, Pavletich, N.P. | | 登録日 | 2005-03-12 | | 公開日 | 2005-04-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54.
Nat.Struct.Mol.Biol., 12, 2005
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5REQ
 | | Methylmalonyl-COA MUTASE, Y89F Mutant, substrate complex | | 分子名称: | COBALAMIN, GLYCEROL, METHYLMALONYL(CARBADETHIA)-COENZYME A, ... | | 著者 | Evans, P.R, Thomae, N.H. | | 登録日 | 1998-08-03 | | 公開日 | 1998-08-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Stabilization of radical intermediates by an active-site tyrosine residue in methylmalonyl-CoA mutase.
Biochemistry, 37, 1998
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1E1C
 | | METHYLMALONYL-COA MUTASE H244A Mutant | | 分子名称: | COBALAMIN, DESULFO-COENZYME A, METHYLMALONYL-COA MUTASE ALPHA CHAIN, ... | | 著者 | Evans, P.R, Thoma, N.H. | | 登録日 | 2000-04-30 | | 公開日 | 2000-05-07 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Protection of Radical Intermediates at the Active Site of Adenosylcobalamin-Dependent Methylmalonyl-Coa Mutase
Biochemistry, 39, 2000
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4A11
 | | Structure of the hsDDB1-hsCSA complex | | 分子名称: | DNA DAMAGE-BINDING PROTEIN 1, DNA EXCISION REPAIR PROTEIN ERCC-8 | | 著者 | Bohm, K, Scrima, A, Fischer, E.S, Gut, H, Thomae, N.H. | | 登録日 | 2011-09-13 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
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1MJE
 | | STRUCTURE OF A BRCA2-DSS1-SSDNA COMPLEX | | 分子名称: | 5'-D(P*TP*TP*TP*TP*TP*T)-3', Deleted in split hand/split foot protein 1, breast cancer 2 | | 著者 | Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P. | | 登録日 | 2002-08-27 | | 公開日 | 2002-09-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Science, 297, 2002
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5NW5
 | | Crystal structure of the Rif1 N-terminal domain (RIF1-NTD) from Saccharomyces cerevisiae in complex with DNA | | 分子名称: | DNA (30-MER), DNA (60-MER), Telomere length regulator protein RIF1 | | 著者 | Bunker, R.D, Reinert, J.K, Shi, T, Thoma, N.H. | | 登録日 | 2017-05-05 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (6.502 Å) | | 主引用文献 | Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends.
Nat. Struct. Mol. Biol., 24, 2017
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7OKQ
 | | Cryo-EM Structure of the DDB1-DCAF1-CUL4A-RBX1 Complex | | 分子名称: | Cullin-4A, DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1, ... | | 著者 | Mohamed, W.I, Schenk, A.D, Kempf, G, Cavadini, S, Thoma, N.H. | | 登録日 | 2021-05-18 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | | 主引用文献 | The CRL4 DCAF1 cullin-RING ubiquitin ligase is activated following a switch in oligomerization state.
Embo J., 40, 2021
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5NVR
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6GVW
 | | Crystal structure of the BRCA1-A complex | | 分子名称: | BRCA1-A complex subunit Abraxas 1, BRCA1-A complex subunit RAP80, BRISC and BRCA1-A complex member 1, ... | | 著者 | Bunker, R.D, Rabl, J, Thoma, N.H. | | 登録日 | 2018-06-21 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | | 主引用文献 | Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.
Mol.Cell, 75, 2019
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6H0F
 | | Structure of DDB1-CRBN-pomalidomide complex bound to IKZF1(ZF2) | | 分子名称: | DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1, DNA-binding protein Ikaros, Protein cereblon, ... | | 著者 | Petzold, G, Bunker, R.D, Thoma, N.H. | | 登録日 | 2018-07-09 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.
Science, 362, 2018
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6H0G
 | | Structure of the DDB1-CRBN-pomalidomide complex bound to ZNF692(ZF4) | | 分子名称: | DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DDB1 (DNA damage binding protein 1),DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ... | | 著者 | Bunker, R.D, Petzold, G, Thoma, N.H. | | 登録日 | 2018-07-09 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (4.25 Å) | | 主引用文献 | Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.
Science, 362, 2018
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6H3C
 | | Cryo-EM structure of the BRISC complex bound to SHMT2 | | 分子名称: | BRISC and BRCA1-A complex member 1, BRISC and BRCA1-A complex member 2, BRISC complex subunit Abraxas 2, ... | | 著者 | Bunker, R.D, Rabl, J, Thoma, N.H. | | 登録日 | 2018-07-18 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.
Mol.Cell, 75, 2019
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6R90
 | | Cryo-EM structure of NCP-THF2(+1)-UV-DDB class A | | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
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6R91
 | | Cryo-EM structure of NCP_THF2(-3)-UV-DDB | | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
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6R92
 | | Cryo-EM structure of NCP-THF2(+1)-UV-DDB class B | | 分子名称: | DNA damage-binding protein 1,DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
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6R8Y
 | | Cryo-EM structure of NCP-6-4PP(-1)-UV-DDB | | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
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6R93
 | | Cryo-EM structure of NCP-6-4PP | | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
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8R1F
 | | Monomeric E6AP-E6-p53 ternary complex | | 分子名称: | Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... | | 著者 | Sandate, C.R, Chakraborty, D, Kater, L, Kempf, G, Thoma, N.H. | | 登録日 | 2023-11-01 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Structural insights into viral hijacking of p53 by E6 and E6AP
Biorxiv, 2023
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8R1G
 | | Dimeric ternary structure of E6AP-E6-p53 | | 分子名称: | Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ... | | 著者 | Sandate, C.R, Chakrabory, D, Kater, L, Kempf, G, Thoma, N.H. | | 登録日 | 2023-11-01 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | | 主引用文献 | Structural insights into viral hijacking of p53 by E6 and E6AP
Biorxiv, 2023
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8P82
 | | Cryo-EM structure of dimeric UBR5 | | 分子名称: | E3 ubiquitin-protein ligase UBR5, ZINC ION | | 著者 | Aguirre, J.D, Kater, L, Kempf, G, Cavadini, S, Thoma, N.H. | | 登録日 | 2023-05-31 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol.Cell, 83, 2023
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8P83
 | | Cryo-EM structure of full-length human UBR5 (homotetramer) | | 分子名称: | E3 ubiquitin-protein ligase UBR5 | | 著者 | Aguirre, J.D, Kater, L, Kempf, G, Cavadini, S, Thoma, N.H. | | 登録日 | 2023-05-31 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol.Cell, 83, 2023
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8OSK
 | | Cryo-EM structure of CLOCK-BMAL1 bound to a nucleosomal E-box at position SHL+5.8 (composite map) | | 分子名称: | Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (124-MER), ... | | 著者 | Stoos, L, Michael, A.K, Kempf, G, Cavadini, S, Thoma, N.H. | | 登録日 | 2023-04-19 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023
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8OSJ
 | | Cryo-EM structure of CLOCK-BMAL1 bound to a nucleosomal E-box at position SHL-6.2 (DNA conformation 1) | | 分子名称: | Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (124-MER), ... | | 著者 | Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N.H. | | 登録日 | 2023-04-19 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023
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6R8Z
 | | Cryo-EM structure of NCP_THF2(-1)-UV-DDB | | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
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6R94
 | | Cryo-EM structure of NCP_THF2(-3) | | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
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