6R92
Cryo-EM structure of NCP-THF2(+1)-UV-DDB class B
Summary for 6R92
Entry DOI | 10.2210/pdb6r92/pdb |
EMDB information | 4766 |
Descriptor | Human alpha-satellite DNA (145-MER), Human alpha-satellite DNA (145-MER) with abasic sites at positions 93-94, DNA damage-binding protein 2, ... (8 entities in total) |
Functional Keywords | dna damage, nucleosome, 6-4 photoproduct, dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 381700.21 |
Authors | Matsumoto, S.,Cavadini, S.,Bunker, R.D.,Thoma, N.H. (deposition date: 2019-04-02, release date: 2019-06-12, Last modification date: 2024-05-22) |
Primary citation | Matsumoto, S.,Cavadini, S.,Bunker, R.D.,Grand, R.S.,Potenza, A.,Rabl, J.,Yamamoto, J.,Schenk, A.D.,Schubeler, D.,Iwai, S.,Sugasawa, K.,Kurumizaka, H.,Thoma, N.H. DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571:79-84, 2019 Cited by PubMed: 31142837DOI: 10.1038/s41586-019-1259-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.8 Å) |
Structure validation
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